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Updated: Jan 20, 2026

Echocardiographic Assessment of Cardiac Anatomy and Function in Adult Rats
Published on: December 13, 2019
The association of anthropometric indices and cardiac function in healthy adults
Javad Shahabi1, Mohammad Garakyaraghi2, Davood Shafie3
1Assistant Professor, Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Insights
Upper body obesity indicators like neck circumference (NC) and waist circumference (WC) correlate with cardiovascular risk factors. These measures, along with body mass index (BMI), are important for estimating metabolic and cardiovascular risks.
Area of Science:
- Cardiology
- Obesity Research
- Diagnostic Imaging
Background:
- Obesity is a significant risk factor for cardiovascular diseases (CVDs).
- Upper body obesity specifically has been identified as a predictor of CVDs.
- This study investigates the link between upper body obesity indicators and echocardiographic measures.
Purpose of the Study:
- To determine the association between upper body obesity indicators and echocardiographic indices.
- To explore the relationship between neck circumference (NC), waist circumference (WC), body mass index (BMI), and cardiac function parameters.
- To assess the predictive value of upper body obesity in cardiovascular health.
Main Methods:
- A cross-sectional study involving 80 healthy adults.
- Measurements included neck circumference (NC), waist circumference (WC), body mass index (BMI), and blood pressure.
- Echocardiography assessed indices like transmitral flow velocity (E, A), diastolic tissue velocity (E', A'), E/E' ratio, pulmonary arterial pressure (PAP), and left atrial volume (LAV).
- Bivariate Pearson correlation coefficients were used to analyze associations.
Main Results:
- In men, NC, WC, and BMI showed significant correlations with LAV, PAP, and blood pressure, with varying impacts on diastolic function indices (E', A).
- In women, NC, WC, and BMI also correlated significantly with LAV and PAP, with additional associations found with ejection fraction (EF) and transmitral flow velocities (E, A).
- Specific correlations included NC with SBP, DBP, A', and negative correlation with E' in men; and NC with LAV, A, EF, SBP, PAP, A', and negative correlation with E' and E/E' in women.
Conclusions:
- Neck circumference (NC), waist circumference (WC), and body mass index (BMI) are positively correlated with left atrial volume (LAV) and pulmonary arterial pressure (PAP) in both sexes.
- The negative correlation of NC with early diastolic tissue velocity (E') highlights its importance.
- These upper body obesity measures are valuable for estimating metabolic and cardiovascular risk factors.
Background:
Obesity is a major risk factor for many diseases including cardiovascular diseases (CVDs). Recently, it has been shown that upper body obesity can predict CVDs per se. In this study, we aimed to determine the association between indicators of upper body obesity and echocardiographic indices.
Methods:
In this cross-sectional study conducted in Hajar Hospital in Shahrekord, Iran, from March to August 2014, 80 healthy adults were included. Participants' neck circumference (NC), waist circumference (WC), body mass index (BMI), and blood pressure were measured. Echocardiography was performed for all participants, and echocardiographic indices such as early (E') and late (A') diastolic tissue velocity, early (E) and late (A) transmitral flow velocity, E/E' ratio, pulmonary arterial pressure (PAP), and left atrial volume (LAV) were recorded. The association between these indices were investigated using bivariate Pearson correlation coefficient.
Results:
For men, NC had a significant correlation with LAV, systolic blood pressure (SBP), diastolic blood pressure (DBP), PAP, and A', and a negative correlation with E'. WC had a significant correlation with LAV, SBP, and PAP, and a negative correlation with E', while BMI had a significant correlation with LAV, PAP, SBP, A, and A'. For women, NC had a significant positive correlation with LAV, A, ejection fraction (EF), SBP, PAP, and A', and a negative correlation with E' and E/E'. WC had a significant positive correlation with LAV, DBP, PAP, A, A', and a negative correlation with E', while BMI had a significant correlation with LAV, EF, SBP, PAP, E', A, and A'.
Conclusion:
The positive correlation of NC with SBP, A, and A', as well as NC, WC, and BMI with LAV and PAP in both sexes, and the negative correlation of NC with E' show the importance of these measures in estimation of metabolic and cardiovascular risk factors.
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