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[A case report of hand, foot, and mouth disease with necrotizing mucocutaneous lesions]
Janett Velástegui1, Ligia Cova2, Yomaira Galarza3
1Hospital General Docente Ambato, Unidad de Pediatría, Ambato, Ecuador. ORCID: 0000-0002-3921-1185.
Abstract:
In most cases, the cause of hand, foot, and mouth disease (HFMD) is coxsackievirus A type 16. The infection can also be caused by other strains of coxsackievirus, spreading mainly by the oral-fecal route, while it is less likely to be transmitted through secretions. HFMD occurs mainly in summer and is more common in children under ten. Skin lesions develop during the disease but rarely become necrotic. When present, they are a severe complication requiring hospitalization. This paper reports the case of a patient with HFMD who developed necrotic mucocutaneous lesions that responded favorably to intravenous acyclovir, fluids, and electrolyte support therapy.
Insights
Hand, Foot, and Mouth Disease (HFMD) typically presents with non-necrotic lesions. This case highlights a rare presentation of necrotic mucocutaneous lesions in HFMD, successfully treated with intravenous acyclovir.
Area of Science:
- Virology
- Dermatology
- Pediatrics
Background:
- Hand, Foot, and Mouth Disease (HFMD) is a common viral illness, usually caused by Coxsackievirus A type 16.
- HFMD typically affects children under ten, primarily during summer months.
- Skin manifestations in HFMD are generally non-necrotic, with necrosis being a rare and severe complication.
Observation:
- This report details a case of HFMD in a patient who developed severe necrotic mucocutaneous lesions.
- Necrotic lesions in HFMD are an uncommon and serious complication.
Findings:
- The patient's necrotic mucocutaneous lesions showed a favorable response to treatment.
- Treatment involved intravenous acyclovir, fluid resuscitation, and electrolyte support.
Implications:
- This case suggests that intravenous acyclovir may be a viable therapeutic option for severe necrotic HFMD complications.
- Further research is warranted to explore the efficacy of antiviral therapies in managing rare HFMD presentations.
- Early recognition and aggressive supportive care are crucial for managing severe HFMD cases with necrotic lesions.
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