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Updated: Jan 20, 2026

A Flow Cytometry-based Assay to Identify Compounds That Disrupt Binding of Fluorescently-labeled CXC Chemokine Ligand 12 to CXC Chemokine Receptor 4
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A Flow Cytometry-based Assay to Identify Compounds That Disrupt Binding of Fluorescently-labeled CXC Chemokine Ligand 12 to CXC Chemokine Receptor 4

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Structural Basis for Allosteric Ligand Recognition in the Human CC Chemokine Receptor 7

Kathrin Jaeger1, Steffen Bruenle1, Tobias Weinert1

  • 1Laboratory of Biomolecular Research, Department of Biology and Chemistry, Paul Scherrer Institute, Villigen PSI.

Cell
|August 24, 2019
PubMed

Keywords:
CCR7G protein-coupled receptorsallosteric modulationcancerchemokine receptorscrystal structurelymph node metastasismembrane proteinsstructure-based drug screening

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