Related Experiment Video
Updated: Jan 20, 2026

Author Spotlight: Deciphering the Long-Term Effects of Low-Level Blast Exposures in Mice
Published on: May 24, 2024
Blast exposure interacts with genetic variant 5HTTLPR to predict posttraumatic stress symptoms in military explosives
Marcus K Taylor1, Lisa M Hernández2, Jeremy Stump2
1Biobehavioral Sciences Lab, Warfighter Performance Department, Naval Health Research Center, San Diego, CA, USA.
Abstract:
The first of its kind, this study determined whether blast exposure interacts with genetic variant 5HTTLPR to predict posttraumatic stress (PTS) symptoms in 78 military explosives operators. In all models, blast-exposed 5HTTLPR S carriers registered definitively higher PTS symptoms in comparison to non-exposed S carriers, as well as exposed and non-exposed LL carriers (all p < 0.01). All findings were robust to confounding influences of age and traumatic brain injury diagnosis. Not only is blast exposure prevalent in EOD personnel, but it also interacts with genetic predisposition to predict trauma symptoms in this unique, at-risk military population.
More Related Videos
Related Concept Videos
Histone Variants at the Centromere
Genetics of Speciation
Predicting Molecular Geometry
Diabetes: Symptoms, Diagnosis, and Complications
Negative and Cognitive Symptoms of Schizophrenia
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Asthma-III: Symptoms and Complications
Classification of Asthma

