Autologous Blood Patch for Persistent Ascites Leak from Non-Closing Paracentesis Tracts

Area of Science:

• Gastroenterology
• Hepatology
• Interventional Procedures

Background:

• Ascites, or peritoneal fluid accumulation, is common in end-stage liver disease (ESLD).
• Paracentesis is used to evaluate or relieve ascites but can lead to leakage.
• Ascites leaks increase patient morbidity and current treatments include medical management or surgery.

Purpose of the Study:

• To evaluate the efficacy of autologous blood patches for managing persistent ascites leaks post-paracentesis.
• To assess the safety and effectiveness of this minimally invasive technique.

Main Methods:

• A prospective case series involving six patients with significant ascites leaks.
• Autologous blood (30 mL) was used to create a blood patch at the paracentesis site.
• Patients were followed for 30 days post-procedure.

Main Results:

• 100% of patients experienced complete resolution of ascites leak within 24 hours.
• No complications were reported following the autologous blood patch procedure.
• The procedure was effective in reducing morbidity associated with ascites leaks.

Conclusions:

• Autologous blood patch is a highly effective and low-risk treatment for ascites leaks.
• This bedside procedure offers a simple alternative to manage post-paracentesis complications.
• It shows promise in reducing morbidity for patients with end-stage liver disease.