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Published on: April 1, 2010
Ictus emeticus induced by photic stimulation
1Department of Medicine, Palmetto General Hospital, Hialeah Hospital, Florida.
Abstract:
It has been recently established that ictus emeticus originates from mesial temporal lobe structures. We herein report a patient with generalized epilepsy who exhibited ictus emeticus reflexly triggered by intermittent photic stimulation accompanied by generalized photoparoxysmal responses on the electroencephalogram. All seizures and EEG abnormalities ceased after treatment with valproic acid. The occurrence of ictus emeticus in generalized epilepsy is an apparent paradox, better explained by the theory of "secondary temporalization" implying the selective engagement of temporal lobe structures during generalized seizures.
Insights
Ictus emeticus, or seizure-induced vomiting, can occur in generalized epilepsy. This phenomenon may be explained by the "secondary temporalization" theory, where temporal lobe structures are engaged during generalized seizures.
Area of Science:
- Neurology
- Epileptology
- Neurophysiology
Background:
- Ictus emeticus (seizure-induced vomiting) is typically associated with mesial temporal lobe epilepsy.
- Generalized epilepsy involves widespread brain dysfunction, not typically focal temporal lobe activity.
Observation:
- A patient with generalized epilepsy experienced ictus emeticus triggered by photic stimulation.
- Electroencephalogram (EEG) showed generalized photoparoxysmal responses during these events.
- Seizures and EEG abnormalities resolved with valproic acid treatment.
Findings:
- The case presents ictus emeticus in the context of generalized epilepsy, a seemingly paradoxical presentation.
- This occurrence supports the theory of 'secondary temporalization'.
- Secondary temporalization suggests that focal temporal lobe structures can become involved during generalized epileptic seizures.
Implications:
- This finding expands the understanding of ictus emeticus triggers and mechanisms.
- It highlights the complex interplay between generalized and focal epileptic networks.
- The study underscores the importance of considering temporal lobe involvement even in generalized epilepsy syndromes.

