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Variations in external reference pricing implementation: does it matter for public policy?
Jennifer Gill1, Anna-Maria Fontrier2, Dionysis Kyriopoulos2
1Department of Health Policy and LSE Health, Medical Technology Research Group, Cowdray House, London School of Economics and Political Science, Houghton Street, London, WC2A 2AE, UK. J.Gill7@lse.ac.uk.
External reference pricing (ERP) aims to control pharmaceutical costs but shows significant variation globally. Harmonizing ERP systems is crucial for sustainable pricing, R&D incentives, and medicine access.
Area of Science:
- Health Economics
- Pharmaceutical Policy
Background:
- External reference pricing (ERP) is a strategy to rationalize pharmaceutical prices using international benchmarks.
- It serves as a basis for negotiations between health authorities and manufacturers.
Purpose of the Study:
- To analyze the characteristics of ERP implementation across 29 countries.
- To benchmark current ERP practices against 14 best practice principles.
Main Methods:
- Systematic literature review to identify ERP implementation characteristics.
- Primary data collection via stakeholder surveys to update or supplement existing data.
- Benchmarking findings against established best practice principles for optimal ERP systems.
Main Results:
- Significant heterogeneity observed in ERP implementation globally.
- Variations noted in country basket size, pricing calculation methods, and frequency of price revisions.
- Belgium, France, and South Africa demonstrated higher adherence to best practices, while Bulgaria, Hungary, and Romania showed more non-adherence.
Conclusions:
- Heterogeneity in ERP impacts global pharmaceutical prices, R&D incentives, and medicine access, particularly in lower-income countries.
- Developing sustainable, transparent, simple, and stable ERP systems is essential.
- Adherence to key guidelines can maximize the benefits of ERP for all stakeholders.
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