A complicated case of bowel obstruction with sepsis and methamphetamine toxicity in a child with pica

Christine Stevens1, Erinn Ton2, Prentiss Jones2

  • 1Western Michigan University Homer Stryker M.D. School of Medicine, 276 Portage Street #200, Kalamazoo, MI, 49007, USA. christine.stevens@med.wmich.edu.

Insights

A pediatric case highlights that children with pica may ingest foreign objects and drugs, leading to bowel obstruction and sepsis. Methamphetamine toxicity can mimic these symptoms, necessitating broader diagnostic considerations in affected children.

Area of Science:

  • Pediatric Toxicology
  • Gastrointestinal Pathology
  • Forensic Medicine

Background:

  • Pica, the persistent eating of non-nutritive, non-food substances, is a recognized condition in children.
  • Accidental drug ingestion is typically considered less common in children over five years old.
  • Bowel obstruction and sepsis are serious conditions in pediatric patients.

Observation:

  • An eleven-year-old female with a history of pica presented with unresponsiveness and was pronounced deceased.
  • Radiologic imaging revealed multiple radio-opaque foreign objects in the gastrointestinal tract.
  • Autopsy confirmed foreign material ingestion and postmortem toxicology identified amphetamine and methamphetamine.

Findings:

  • The autopsy findings were consistent with bowel obstruction and sepsis secondary to foreign material ingestion.
  • High methamphetamine concentrations suggested concurrent methamphetamine toxicity.
  • Methamphetamine toxicity and bowel obstruction can present with similar clinical signs in children.

Implications:

  • The age range for suspecting accidental drug ingestion should be expanded for children with pica.
  • Pediatric patients with pica presenting with bowel obstruction symptoms warrant consideration for unintentional drug ingestion.
  • Awareness of potential co-occurrence of pica-related foreign body ingestion and drug toxicity is crucial, especially in environments with substance abuse.

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