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Androgen receptor splicing variant 7: Beyond being a constitutively active variant

Chen Shao1, Bingbing Yu1, Yanan Liu1

  • 1Department of Pathophysiology, College of Basic Medical Sciences, Jilin University, Changchun, China.

Life Sciences
|August 25, 2019
PubMed
Summary

Androgen receptor (AR) signaling drives prostate cancer. AR-V7, a variant of the AR, promotes resistance to therapies and is a key target for treating advanced prostate cancer.

Keywords:
Androgen receptorAndrogen receptor splicing variant 7Prostate cancerTaxanesTranscriptional regulation

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