Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sleep Apnea01:21

Sleep Apnea

487
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
487
Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

850
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
850
Autonomic Nervous System01:22

Autonomic Nervous System

12.3K
The autonomic nervous system (ANS) is a critical component of the peripheral nervous system, primarily responsible for regulating involuntary bodily functions and maintaining homeostasis. It functions in tandem with the central nervous system (CNS) to seamlessly coordinate various physiological processes without the need for conscious control.
The ANS comprises two main divisions: the sympathetic and parasympathetic divisions. These divisions function antagonistically to maintain a dynamic...
12.3K
Stages of Sleep01:22

Stages of Sleep

1.3K
Sleep progresses through distinct stages, each characterized by specific brain wave patterns and physiological responses ranging from wakefulness to stages of non-rapid eye movement, known as non-REM, to rapid eye movement, referred to as REM. Understanding these stages helps in recognizing how sleep supports various bodily and cognitive functions.
Before sleep begins, in wakefulness, the brain exhibits primarily beta waves, which are high in frequency and low in amplitude, indicating alertness...
1.3K
Autonomic Nervous System: Overview01:26

Autonomic Nervous System: Overview

7.3K
The human nervous system is divided into two main parts: the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS is composed of the brain and spinal cord, while the PNS contains nerve cells, clusters of nerve cells, and the sensory receptors that are outside the CNS. The PNS has two types of nerve cells: sensory (afferent) and motor (efferent). Sensory cells send signals to the CNS from receptors, and motor cells carry signals from the CNS to organs, muscles, and...
7.3K
Disorders of the Autonomic Nervous System01:18

Disorders of the Autonomic Nervous System

1.4K
The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
Raynaud's disease, also known as Raynaud's...
1.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

When the Solution May Be Worse Than the Problem: A Caution Against Permanent Daylight Saving Time, on Behalf of the Italian Academy of Sleep Medicine.

Journal of sleep research·2026
Same author

Plasma PCSK9 levels in children and adolescents: evidence from an Italian outpatient paediatric clinic cohort at cardio-metabolic risk.

Nutrition, metabolism, and cardiovascular diseases : NMCD·2026
Same author

Right ventricular reserve in cardiopulmonary disease: A simultaneous hemodynamic and three-dimensional echocardiographic study.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2024
Same author

Candidacy and long-term outcomes of subcutaneous implantable cardioverter-defibrillators in current practice in patients with hypertrophic cardiomyopathy.

International journal of cardiology·2024
Same author

Chronic rhinosinusitis with nasal polyposis and biological agents: the ARIA-ITALY survey.

European annals of allergy and clinical immunology·2024
Same author

Congenital high airway obstruction syndrome in mid-trachea: endotracheal bronchogenic cyst.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2024
Same journal

The co-existence of Ehlers-Danlos syndrome and postural orthostatic tachycardia syndrome: A systematic review of the literature.

Autonomic neuroscience : basic & clinical·2026
Same journal

Urodynamics and what they reveal about autonomic innervation of the lower urinary tract: A narrative review.

Autonomic neuroscience : basic & clinical·2026
Same journal

Pelvic venous disorders and orthostatic intolerance: A systematic review of diagnostic associations and treatment outcomes.

Autonomic neuroscience : basic & clinical·2026
Same journal

Application of heart rate variability in clinical practice and research: A systematic review of recent years.

Autonomic neuroscience : basic & clinical·2026
Same journal

Spinal afferent endings in the gastrointestinal tract.

Autonomic neuroscience : basic & clinical·2026
Same journal

Gastric myoelectrical activity and autonomic dysfunction in children with IBD and IBS: An electrogastrographic and autonomic correlation study.

Autonomic neuroscience : basic & clinical·2026
See all related articles

Related Experiment Video

Updated: Jan 20, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

20.5K

Obstructive sleep apnea syndrome and autonomic dysfunction.

C Lombardi1, M F Pengo2, G Parati1

  • 1Istituto Auxologico Italiano, IRCCS, Sleep Disorders Center & Department of Cardiovascular, Neural and Metabolic Sciences, San Luca Hospital, Milan, Italy; Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.

Autonomic Neuroscience : Basic & Clinical
|August 25, 2019
PubMed
Summary
This summary is machine-generated.

Obstructive sleep apnea (OSA) is linked to autonomic nervous system (ANS) dysfunction, particularly sympathetic overactivity. OSA treatment can reverse these autonomic changes, highlighting the ANS

More Related Videos

Multi-Modal Home Sleep Monitoring in Older Adults
07:40

Multi-Modal Home Sleep Monitoring in Older Adults

Published on: January 26, 2019

8.1K
Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders
05:34

Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders

Published on: August 18, 2023

3.3K

Related Experiment Videos

Last Updated: Jan 20, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

20.5K
Multi-Modal Home Sleep Monitoring in Older Adults
07:40

Multi-Modal Home Sleep Monitoring in Older Adults

Published on: January 26, 2019

8.1K
Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders
05:34

Author Spotlight: Utilizing Traditional Chinese Acupuncture of the Ear to Improve Sleep Disorders

Published on: August 18, 2023

3.3K

Area of Science:

  • Physiology
  • Sleep Medicine
  • Autonomic Neuroscience

Background:

  • The autonomic nervous system (ANS) plays a crucial role in maintaining bodily homeostasis and responding to stressors.
  • Obstructive sleep apnea (OSA) is increasingly recognized for its impact on physiological systems.
  • Previous research has indicated autonomic alterations in OSA patients, primarily focusing on cardiovascular effects.

Purpose of the Study:

  • To explore the multifaceted impact of obstructive sleep apnea (OSA) on the autonomic nervous system (ANS).
  • To review existing methodologies for assessing ANS function in OSA patients.
  • To highlight the need for a broader understanding of ANS involvement beyond cardiovascular consequences.

Main Methods:

  • Review of studies employing microneurography for direct ANS function assessment.
  • Analysis of baroreflex sensitivity (BRS) using sequence and cross-spectral methods.
  • Evaluation of heart rate variability (HRV) in time and frequency domains during sleep and wakefulness.
  • Inclusion of conventional laboratory tests like the cold pressor test, hand grip test, and urinary catecholamine excretion measurements.

Main Results:

  • Consistent evidence of ANS alterations in OSA patients, notably sympathetic overactivity.
  • Demonstration of both acute (during apnea events) and chronic (daytime) sympathetic overactivity.
  • Indication of a dose-response relationship between OSA severity and sympathetic overactivity.
  • Evidence suggesting reversibility of sympathetic overactivity with OSA treatment.

Conclusions:

  • Autonomic dysfunction, particularly sympathetic overactivity, is a significant consequence of obstructive sleep apnea.
  • The observed autonomic alterations are implicated in the cardiovascular complications associated with OSA.
  • Further research is required to fully elucidate the short- and long-term effects of sleep-disordered breathing on the broader functions regulated by the ANS.