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Blood Flow Imaging with Ultrafast Doppler

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Nonlinear sampling in ultrafast Laplace NMR.

Vladimir V Zhivonitko¹, Md Sharif Ullah¹, Ville-Veikko Telkki¹

¹NMR Research Unit, University of Oulu, P.O. Box 3000, 90014 Oulu, Finland.

Journal of Magnetic Resonance (San Diego, Calif. : 1997)

|August 25, 2019

Summary

Ultrafast Laplace Nuclear Magnetic Resonance (UF-LNMR) speeds up experiments. A new nonlinear sampling method with frequency-swept pulses improves resolution for relaxation and diffusion measurements.

Keywords:

Laplace NMR NMR relaxation Non-uniform sampling Ultrafast NMR

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Area of Science:

Nuclear Magnetic Resonance (NMR) Spectroscopy
Physical Chemistry
Materials Science

Background:

Multidimensional relaxation and diffusion measurements in NMR are time-consuming.
Ultrafast Laplace Nuclear Magnetic Resonance (UF-LNMR) significantly reduces experiment duration.
Optimizing data acquisition is crucial for enhancing NMR parameter resolution.

Purpose of the Study:

To introduce a novel nonlinear sampling strategy for the indirect dimension in UF-LNMR.
To demonstrate the application of frequency-swept pulses for optimized data acquisition.
To improve the resolution of NMR parameters obtained from relaxation and diffusion measurements.

Main Methods:

Implementation of nonlinear (logarithmic) sampling in the indirect dimension of UF-LNMR experiments.
Utilizing frequency-swept pulses with a nonlinear time-dependent frequency increase.
Acquisition and processing of exponential experimental data.

Main Results:

Successful demonstration of nonlinear sampling in UF-LNMR.
Optimized detection of exponential experimental data.
Significantly improved resolution of Laplace Nuclear Magnetic Resonance (LNMR) parameters.

Conclusions:

Nonlinear sampling with frequency-swept pulses is an effective method for UF-LNMR.
This approach enhances the efficiency and resolution of multidimensional NMR measurements.
The method offers a significant advancement for relaxation and diffusion studies.