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Structure based design of macrocyclic factor XIa inhibitors: Discovery of cyclic P1 linker moieties with improved

Charles G Clark1, Karen A Rossi1, James R Corte1

  • 1Bristol-Myers Squibb Company, P.O. Box 4000, Princeton, NJ 08543, United States.

Bioorganic & Medicinal Chemistry Letters
|August 26, 2019
PubMed

Keywords:
Activated partial thromboplastin timeAnticoagulantBioavailabilityFXIaFactor XIa inhibitorsThrombosisaPTT

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