Related Experiment Video

Updated: Jan 20, 2026

Expression and Purification of Virus-like Particles for Vaccination
06:17

Expression and Purification of Virus-like Particles for Vaccination

Published on: June 2, 2016

22.7K

Advances in Vaccines

Helen H Mao1, Shoubai Chao2

  • 1CanSino Biologics Inc., Tianjin, China. helen.mao@cansinotech.com.

Advances in Biochemical Engineering/Biotechnology
|August 26, 2019
PubMed

Insights

Vaccine development advances are crucial for preventing infectious diseases globally. Despite progress, significant vaccination gaps persist, impacting millions of children and highlighting the need for improved vaccine access and new disease preventatives.

Area of Science:

  • Immunology
  • Public Health
  • Medical Science

Background:

  • Vaccines are vital for controlling infectious diseases, yet global vaccination coverage remains incomplete.
  • Significant numbers of children in the EU and worldwide miss essential vaccine doses, such as diphtheria, pertussis, and tetanus (DPT).
  • Rising cases of measles in Europe and the US, alongside threats from emerging diseases like malaria, Ebola, and Zika, underscore ongoing public health challenges.

Purpose of the Study:

  • To provide a comprehensive overview of recent advancements in vaccine development and technology.
  • To discuss the manufacturing, characterization, and clinical development strategies for various vaccines.
  • To highlight challenges and approved vaccines for human use.

Main Methods:

  • Review of recent scientific literature and public health data on vaccination rates and disease incidence.
  • Analysis of emerging infectious diseases and their global impact.
  • Examination of current vaccine technologies, manufacturing processes, and clinical trial methodologies.

Main Results:

  • Identified substantial gaps in routine childhood vaccination coverage in regions like the EU.
  • Documented increasing incidence of vaccine-preventable diseases, such as measles.
  • Highlighted the threat posed by emerging infectious diseases requiring novel vaccine solutions.

Conclusions:

  • Advances in vaccine science are critical for addressing persistent and emerging infectious disease threats.
  • Improved strategies are needed to enhance global vaccine access and achieve higher vaccination coverage rates.
  • Ongoing research and development in vaccine technologies are essential for public health security.

Keywords:
CharacterizationDengue vaccineEbola vaccineRecombinant technologyShingles vaccineVaccine clinical trialsVaccine developmentVaccine manufacturingViral vaccine

More Related Videos

Detection of Polyfunctional T Cells in Children Vaccinated with Japanese Encephalitis Vaccine via the Flow Cytometry Technique09:37

Detection of Polyfunctional T Cells in Children Vaccinated with Japanese Encephalitis Vaccine via the Flow Cytometry Technique

Published on: September 23, 2022

2.2K
Intralymphatic Immunotherapy and Vaccination in Mice07:33

Intralymphatic Immunotherapy and Vaccination in Mice

Published on: February 2, 2014

23.9K

Related Concept Videos

Vaccinations01:51

Vaccinations

Overview
51.3K
Cancer Vaccines01:30

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
978
Extraction: Advanced Methods00:56

Extraction: Advanced Methods

Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
1.1K
Overview of Advanced Functional Groups02:22

Overview of Advanced Functional Groups


Functional groups are groups of atoms with specific chemical properties that occur within organic molecules and are sometimes denoted as “R”. Functional groups can “functionalize” a compound by enabling it to adopt different physical and chemical properties.
Types of Advanced Functional Groups
The table below summarizes some of the major functional groups in organic chemistry.
29.2K
Sample Preparation for Analysis: Advanced Techniques01:08

Sample Preparation for Analysis: Advanced Techniques

Accurate analysis of complex samples often requires advanced preparation techniques to achieve reliable and reproducible results. Samples containing inorganic or organic materials can be challenging to dissolve or decompose effectively. Standard sample preparation methods include acid digestion, fusion, dry ashing, and wet digestion.
Acid digestion with strong acids is commonly used to dissolve inorganic materials that are insoluble (do not dissolve) in water. This method can be useful for...
1.3K
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques01:30

Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques

Airway management is essential in emergency and surgical medicine, ensuring ventilation and oxygenation in patients who cannot maintain their own airway. Clinicians use a range of techniques and devices to secure the airway, depending on the patient’s condition and the clinical context. Key methods include endotracheal intubation, rapid sequence intubation (RSI), supraglottic airway devices, and advanced visualization aids. In cases where these approaches fail, surgical airway...
488