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Clinicians' Guide to Cannabidiol and Hemp Oils
Harrison J VanDolah1, Brent A Bauer2, Karen F Mauck3
1Creighton University School of Medicine, Omaha, NE.
Mayo Clinic Proceedings
|August 27, 2019
Summary
Cannabidiol (CBD) oils show promise for various conditions, including pain and addiction, without the psychoactive effects of marijuana. However, inconsistent product labeling necessitates careful selection of high-quality CBD and hemp oil formulations.
Area of Science:
- Pharmacology
- Natural Products Chemistry
- Clinical Therapeutics
Background:
- Cannabidiol (CBD) oils, derived from Cannabis sativa, are increasingly popular for therapeutic use.
- Patients report benefits for pain and other conditions, distinct from the psychoactive effects of tetrahydrocannabinol (THC).
- The FDA approval of Epidiolex for epilepsy highlights the growing recognition of CBD's medical potential.
Purpose of the Study:
- To provide an overview of scientific research on cannabinoids, CBD, and hemp oil.
- To clarify the distinctions between marijuana, hemp, and their respective oil components.
- To guide clinicians in advising patients on safe and effective CBD product selection.
Main Methods:
- Literature review based on a PubMed search.
- Keywords included CBD, cannabidiol, hemp oil, and medical marijuana.
- Articles were screened for relevance and recency.
Main Results:
- Growing preclinical and clinical evidence supports CBD oil use for conditions like chronic pain and opioid addiction.
- Significant regulatory concerns exist due to inaccurate product labeling regarding CBD and THC content.
- The legal status of CBD and hemp oils in the US is summarized.
Conclusions:
- CBD and hemp oils offer potential therapeutic benefits but require careful consideration due to regulatory gaps.
- Clinicians need guidance to identify high-quality products for patient recommendations.
- Further research and standardization are crucial for the safe and effective use of CBD products.