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Multienzymatic Nanoassemblies: Recent Progress and Applications.
Archontoula Giannakopoulou1, Elena Gkantzou1, Angeliki Polydera1
1Laboratory of Biotechnology, Department of Biological Applications and Technology, University of Ioannina, Ioannina, Greece.
Trends in Biotechnology
|August 27, 2019
Summary
Multienzymatic nanoassemblies offer powerful biocatalytic systems for diverse applications. Research highlights their optimization and use in biosensing, pharmaceuticals, and biopolymer conversion, showcasing future industrial potential.
Area of Science:
- Biotechnology
- Biocatalysis
- Nanotechnology
Background:
- Multienzymatic nanoassemblies are emerging as key platforms in biotechnological research.
- These systems enable the integration of multiple enzymes for complex catalytic processes.
Purpose of the Study:
- To review the development and optimization of multienzymatic nanoassemblies.
- To present advances in bi- and multienzymatic cascade reactions for various industrial applications.
- To highlight the future potential of these biocatalytic systems.
Main Methods:
- Discussion of co-immobilization techniques for enzyme integration.
- Analysis of parameters influencing multienzymatic cascade reaction performance.
- Presentation of continuous flow processes with nanoassemblies in various reactor configurations.
Main Results:
- Demonstration of applications in ultrasensitive biosensing.
- Advancements in pharmaceutical development using these systems.
- Successful conversion of natural biopolymers into valuable products.
Conclusions:
- Multienzymatic nanoassemblies provide innovative tools for biocatalysis.
- These systems offer new possibilities for the chemical, biotechnological, and pharmaceutical industries.
- Further development promises more effective and versatile biocatalyst applications.
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