Related Experiment Video
Updated: Jan 20, 2026

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
[Giant subcutaneous metastasis originating from vesicular thyroid carcinoma: about a case]
Ny Ony Tiana Andrianandrasana1, Malala Razakanaivo1, Marie Ida Rahantamalala2
1Service Oncologie-Radiothérapie, Hôpital Joseph Ravoahangy Andrianavalona CHU Antananarivo, Madagascar.
Abstract:
Secondary subcutaneous metastasis originating from vesicular thyroid carcinoma is unusual. It accounts for more than 5.8% of most common sites of metastasis for thyroid carcinoma. We here report the case of a 60-year old woman presenting with slowly evolving giant hypervascular lesion in the subcutaneous tissue of the skull occurred 7 years after right thyroid lobectomy. Anatomopathological examination enabled the diagnosis of vesicular thyroid carcinoma. Surgery was based on reduction of the skull lesion as well as on thyroidectomy. Currently, the patient is waiting for radioactive iodine treatment. Metastasis from vesicular carcinoma of the scalp, even though rare, can occur. However, this stage is associated with unfavorable prognosis.
More Related Videos
05:06A "Patient-Like" Orthotopic Syngeneic Mouse Model of Hepatocellular Carcinoma Metastasis
Published on: October 24, 2015
08:17Murine Experimental Model of Original Tumor Development and Peritoneal Metastasis via Orthotopic Inoculation with Ovarian Carcinoma Cells
Published on: December 9, 2016
Related Concept Videos
Vesicular Tubular Clusters
With the help of motor proteins such...
Metastasis
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Vesicular Trasport: Endocytosis, Transcytosis and Exocytosis
Endocytosis is a cellular mechanism that involves the inward folding of the cell membrane to create vesicles that capture and transport large drug molecules. This process comprises two distinct methods: pinocytosis (often referred to as "cell drinking") and phagocytosis (often referred to as "cell...
The Thyroid Gland
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Functions of Thyroid Hormones
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
Mechanisms of Drug Absorption: Paracellular, Transcellular, and Vesicular Transport
However, most drugs use the transcellular route, traversing directly through the cell membranes via two mechanisms: passive and active transport. Passive...