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Production and Targeting of Monovalent Quantum Dots
Published on: October 23, 2014
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Quantum Dots in Ophthalmology: A Literature Review
Sidra Sarwat1, Fiona Stapleton1, Mark Willcox1
1School of Optometry and Vision Science, University of New South Wales (UNSW) , Sydney , Australia.
Current Eye Research
|August 27, 2019
Summary
Quantum dots offer promising applications in ophthalmology for bioimaging and drug delivery. Further research is needed to fully understand their characteristics and safety for ocular use.
Area of Science:
- Ophthalmology
- Nanotechnology
- Biomedical Engineering
Background:
- Quantum dots are semiconductor nanocrystals with unique optical properties.
- Their fluorescence makes them suitable for bioimaging and labeling applications.
Purpose of the Study:
- To review current applications of quantum dots in ophthalmology.
- To highlight recent advances and identify research gaps in this field.
Main Methods:
- Systematic literature search following PRISMA guidelines.
- Searched PubMed, MEDLINE, Scopus, Embase, and Web of Science.
- Included 22 eligible articles from an initial 280.
Main Results:
- Quantum dots show potential for diagnostic and therapeutic uses in ophthalmology.
- Their visible and near-infrared emission is ideal for bioimaging due to low light scattering and tissue absorption.
- Applications include in vivo bioimaging, cell/tissue labeling, gene/drug delivery, and antimicrobial composites.
Conclusions:
- Quantum dots have been utilized in ophthalmology for bioimaging, electrical stimulation, cell tracking, and lymphatic studies.
- Key research gaps include a lack of detailed characterization for ophthalmology and limited data on ocular cytotoxicity.
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