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Opportunities for improving use of evidence-based therapy in patients with type 2 diabetes and cardiovascular disease
Yumin Gao1, Eric Peterson2, Neha Pagidipati2
1Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Abstract:
Evidence-based therapy that target hyperlipidemia, hypertension, smoking cessation, and weight loss have demonstrated significant benefits in reducing cardiovascular risks and related events. Although the benefit of intensively lowering blood glucose is unclear, newer antidiabetic drugs (glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter-2 inhibitors) have shown cardiovascular benefits in addition to their antihyperglycemic effect. Yet, studies suggest that recent use of evidence-based therapy and management of cardiovascular risk among individuals with type 2 diabetes (T2D) and cardiovascular disease (CVD) remains largely suboptimal. The following narrative review first identifies barriers to translating research evidence to clinical practice at the levels of provider, health system, patient, and cost. Then it synthesizes previous implementation strategies that addressed multifaceted barriers and attempted to improve care for patients with T2D and CVD. In conclusion, team-based care coordination, reminding systems in combination to pharmacist consultation and patient education, provider education compatible with clinical workflow, and coupled incentives between providers and patients appeared to be effective in reducing cardiovascular risks for patients with T2D and CVD, though the scalability and long-term clinical effect of these strategies as well as the possibility of interventions involving payers and health systems remain uncertain.
Insights
Implementing evidence-based therapies for type 2 diabetes (T2D) and cardiovascular disease (CVD) remains suboptimal. Strategies like team-based care and patient education show promise in reducing cardiovascular risks, but scalability is uncertain.
Area of Science:
- Cardiology
- Endocrinology
- Health Services Research
Background:
- Cardiovascular risk reduction therapies (e.g., for hyperlipidemia, hypertension, smoking cessation, weight loss) significantly benefit patients.
- While intensive glucose lowering's benefit is unclear, newer antidiabetic drugs show cardiovascular advantages.
- Management of cardiovascular risk in type 2 diabetes (T2D) and cardiovascular disease (CVD) patients is often suboptimal.
Purpose of the Study:
- Identify barriers to translating evidence-based cardiovascular risk reduction therapies into clinical practice for T2D and CVD patients.
- Synthesize implementation strategies to improve care for this population.
Main Methods:
- Narrative review identifying barriers at provider, health system, patient, and cost levels.
- Synthesis of previous implementation strategies targeting these barriers.
Main Results:
- Barriers to evidence translation include provider, system, patient, and cost factors.
- Effective strategies include team-based care coordination, reminder systems, pharmacist consultation, patient education, provider education, and coupled provider-patient incentives.
- These strategies showed effectiveness in reducing cardiovascular risks for T2D and CVD patients.
Conclusions:
- Team-based care, patient education, and provider education are effective in reducing cardiovascular risks for T2D and CVD patients.
- The scalability and long-term clinical impact of these strategies require further investigation.
- The role of payers and health systems in interventions remains uncertain.
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