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Diabetic cardiomyopathy: acute and reversible left ventricular systolic dysfunction due to cardiotoxicity of

Umut Kocabaş1, Özgür Yılmaz2, Volkan Kurtoğlu2

  • 1Department of Cardiology, Başkent University Faculty of Medicine, Istanbul, Turkey.

European Heart Journal. Case Reports
|August 27, 2019
PubMed

Insights

Diabetic cardiomyopathy can cause acute heart dysfunction. Controlling blood sugar is key to preventing diabetic cardiomyopathy and improving heart function in hyperglycaemic crises.

Area of Science:

  • Cardiology
  • Endocrinology
  • Diabetology

Background:

  • Diabetic cardiomyopathy (DC) is ventricular dysfunction linked to diabetes mellitus (DM).
  • Excludes other causes like heart disease or alcoholism.
  • Presents a case of DC with reversible left ventricular dysfunction from hyperosmolar hyperglycaemic state (HHS).

Purpose of the Study:

  • To report an unusual case of diabetic cardiomyopathy.
  • To highlight reversible left ventricular dysfunction caused by hyperosmolar hyperglycaemic state.

Main Methods:

  • A 20-year-old male with symptoms of HHS.
  • Echocardiography revealed left ventricular hypokinesis (EF 36%).
  • Monitored cardiac function during blood glucose normalization.

Main Results:

  • Patient presented with weakness and polyuria, diagnosed with HHS.
  • Initial echocardiogram showed severe systolic dysfunction (EF 36%).
  • Follow-up echocardiograms showed progressive recovery of left ventricular function (EF 54% at 5 days, 69% at 15 days).

Conclusions:

  • Uncontrolled diabetes and hyperglycaemic crises can cause cardiotoxicity and acute left ventricular dysfunction.
  • The exact mechanism of this cardiotoxicity remains unclear.
  • Effective blood glucose control is crucial for preventing diabetic cardiomyopathy.
Abstract

Keywords:
CardiotoxicityCase reportDiabetic cardiomyopathyHyperglycaemic crisisSystolic dysfunction

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