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Disseminated melioidosis with native valve endocarditis: a case report
Hariharan Subramony1, Sengottuvelu Gunasekaran2, Vinodh Kumar Paul Pandi2
1Department of General Medicine, Apollo Hospital, Greams Road, Chennai, Tamil Nadu, India.
European Heart Journal. Case Reports
|August 27, 2019
Summary
Melioidosis, a bacterial infection, can rarely affect the heart valves, leading to infective endocarditis. This case highlights an unusual presentation of this emerging disease in India.
Area of Science:
- Infectious Diseases
- Bacteriology
- Cardiology
Background:
- Burkholderia pseudomallei is a Gram-negative bacterium endemic in Southeast Asia and Northern Australia.
- Melioidosis, the disease caused by B. pseudomallei, is increasingly diagnosed in regions like India.
- The clinical presentation of melioidosis is highly variable.
Purpose of the Study:
- To report a rare case of melioidosis presenting as native valve infective endocarditis.
- To highlight the unusual clinical manifestations of an emerging infectious disease.
Main Methods:
- Case report presentation.
- Review of clinical findings and relevant literature.
Main Results:
- A patient presented with native valve infective endocarditis, hepatic abscess, and splenic abscess.
- This represents the second reported case of melioidosis with infective endocarditis from India.
Conclusions:
- Melioidosis typically presents with diverse symptoms, but cardiac involvement, particularly endocarditis, is rare (approximately 1%).
- This case underscores the importance of considering melioidosis in the differential diagnosis of infective endocarditis, especially in endemic or emerging regions.
- The unusual presentation emphasizes the diagnostic challenges posed by this emerging infectious disease.
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