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Surface Properties of Synthesized Nanoporous Carbon and Silica Matrices
Published on: March 27, 2019
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Polyphenols extract from grape pomace. Characterization and valorisation through encapsulation into mesoporous
Ana-Maria Brezoiu1, Cristian Matei1, Mihaela Deaconu1
1University "Politehnica" of Bucharest, Faculty of Applied Chemistry and Material Sciences, 1-7 Gheorghe Polizu Street, Bucharest, 011061, Romania.
Summary
Grape pomace polyphenols were encapsulated into silica matrices to improve stability and antioxidant activity. Encapsulated extracts showed enhanced radical scavenging and good cytocompatibility with human skin cells.
Area of Science:
- Materials Science
- Food Chemistry
- Biotechnology
Background:
- Grape pomace is rich in polyphenols with antioxidant properties.
- Polyphenolic extracts are sensitive to degradation, limiting their application.
- Mesoporous silica MCM-41 offers a stable matrix for bioactive compound encapsulation.
Purpose of the Study:
- To encapsulate grape pomace polyphenolic extracts into MCM-41 silica matrices.
- To enhance the stability and radical scavenger activity of the extracts.
- To evaluate the cytocompatibility of the encapsulated extracts.
Main Methods:
- Ethanolic extraction of polyphenols from grape pomace (Cabernet Sauvignon, Feteasca Neagra, grape skins).
- Microwave-assisted extraction and conventional extraction methods were employed.
- Encapsulation into pristine, Zn-modified, and Mg-modified MCM-41 silica matrices.
- Analysis of polyphenol composition using HPLC, Folin-Ciocalteu, AlCl3 complexation, and anthocyanin assays.
- Assessment of radical scavenger activity using a solid-state DPPH assay.
- Cytocompatibility testing on HaCaT keratinocyte human cells.
Main Results:
- Encapsulation into MCM-41, Zn-MCM-41, and Mg-MCM-41 matrices enhanced radical scavenger activity.
- The stability of the polyphenolic extracts was improved by encapsulation.
- Free and encapsulated Cabernet Sauvignon and grape skins extracts demonstrated good cytocompatibility with HaCaT cells.
Conclusions:
- Mesoporous silica matrices effectively stabilize grape pomace polyphenols.
- Encapsulation preserves and enhances the antioxidant capacity of these extracts.
- The developed encapsulated polyphenols are suitable for potential applications in cosmetics or nutraceuticals due to their cytocompatibility.
Keywords:
Encapsulated extractGrape pomace extractMesoporous silicaMicrowave-assisted extractionPhenolic extractMore Related Videos
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