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Updated: Jan 20, 2026

Isolation and Characterization of Tumor-initiating Cells from Sarcoma Patient-derived Xenografts
Published on: June 13, 2019
Undifferentiated pleomorphic sarcoma presenting as an exophytic pedunculated tumor on the left scapula
A Cerejeira1, N Gomes, M Costa-Silva
1Department of Dermatology and Venereology, Centro Hospitalar São João, EPE Porto. andrecerejeira_@hotmail.com.
Abstract:
Undifferentiated pleomorphic sarcoma is a common soft tissue sarcoma. Unfortunately, any attempt to describe the line of differentiation fails. It represents a final common pathway in tumors that undergoes progression towards dedifferentiation. We report a man with an undifferentiated pleomorphic sarcoma presenting as an exophytic pedunculated tumor of the left scapula. Histopathology analysis revealed spindle-shaped cells with great pleomorphism and numerous mitoses. Immunohistochemistry showed diffuse expression of vimentin. Wide local excision was performed after an oncology consultation. After two-years of follow-up, the patient has shown no evidence of recurrence or metastases.
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