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Updated: Jan 20, 2026

Transfecting and Nucleofecting Human Induced Pluripotent Stem Cells
Published on: October 5, 2011
Modeling Leukemia with Human Induced Pluripotent Stem Cells
Eirini P Papapetrou1,2,3,4
1Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA eirini.papapetrou@mssm.edu.
Abstract:
The reprogramming of human somatic cells into induced pluripotent stem cells (iPSCs) a little over a decade ago raised exciting prospects to transform the study and potentially also the therapy of human diseases. iPSC models have now been created for a multitude of hematologic diseases, including malignancies. Here we discuss practical aspects of iPSC modeling of malignant diseases, review recent studies, and discuss the new opportunities that iPSC models offer, as well as their current limitations and prospects for future development.
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