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Related Concept Videos

Cis-regulatory Sequences02:02

Cis-regulatory Sequences

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Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments serve as binding sites for transcriptional regulators, proteins that are responsible for controlling gene transcription and differential gene expression across cell types in eukaryotes. Cis-regulatory sequences can be close to the gene of interest or thousands of bases away in the DNA sequence; however, those sequences that are further away are...
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The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
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An ideal Y-Y transformer, grounded through neutral impedances, displays per-unit sequence networks akin to those of a single-phase ideal transformer when subjected to balanced positive- or negative-sequence currents. These currents do not produce neutral currents, and their associated voltage drops.
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Updated: Jan 20, 2026

Sequencing of mRNA from Whole Blood using Nanopore Sequencing
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Bioinformatics of nanopore sequencing.

Wojciech Makałowski1, Victoria Shabardina2

  • 1Institute of Bioinformatics, Faculty of Medicine, University of Münster, 48149, Münster, Germany. wojmak@uni-muenster.de.

Journal of Human Genetics
|August 28, 2019
PubMed
Summary

Nanopore sequencing technology is rapidly advancing, offering new analytical tools for researchers. This guide reviews available software to help scientists analyze nanopore sequencing data effectively.

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Area of Science:

  • Genomics
  • Bioinformatics

Background:

  • Nanopore sequencing is a rapidly developing technology.
  • The increasing use of nanopore sequencing has led to a proliferation of analytical tools.

Purpose of the Study:

  • To provide an overview of available software for analyzing nanopore sequencing data.
  • To assist researchers in navigating the evolving landscape of nanopore bioinformatics tools.

Main Methods:

  • Literature review of current bioinformatics software.
  • Categorization and description of tools based on analytical functions.

Main Results:

  • A comprehensive list of software for nanopore sequence analysis is presented.
  • Key features and applications of various tools are discussed.

Conclusions:

  • Researchers can effectively analyze nanopore sequencing data with the right tools.
  • This review serves as a valuable resource for selecting appropriate bioinformatics software.