Acute effects of centrophenoxine short term administration on counting behavior in rats

This experiment assessed the effects of Centrophenoxine on counting behavior in rats. Intraperitoneal Centrophenoxine injections were given to rats before training on a 20-fixed-consecutive-number schedule of reinforcement. The primary measure was the number of consecutive lever presses. After Centrophenoxine injections, the number of consecutive lever presses was lower relative to baseline measures. The measures of variability indicated that although the consecutive number of responses was lower this could not be accounted for in terms of run length variability. The behavioral pattern produced by the injections was discussed in terms of possible shortterm physiological effects that affect performance.