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Cerebral oximetry performance testing with a 3D-printed vascular array phantom.

Ali Afshari1, Pejman Ghassemi1, Jonathan Lin1

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|August 28, 2019
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This summary is machine-generated.

A novel 3D-printed phantom accurately tests cerebral oximetry devices. This cerebrovascular module (CVM) aids in developing standardized performance testing for near-infrared spectroscopy (NIRS) systems used in surgery.

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Area of Science:

  • Biomedical Engineering
  • Medical Physics
  • Surgical Technology

Background:

  • Cerebral oximetry using near-infrared spectroscopy (NIRS) is a vital noninvasive surgical monitoring tool.
  • Significant accuracy discrepancies exist among commercial NIRS oximeters, necessitating standardized performance testing.

Purpose of the Study:

  • To develop and characterize a 3D-printed solid phantom, a cerebrovascular module (CVM), for standardized performance testing of NIRS cerebral oximeters.
  • To evaluate the accuracy and precision of commercial NIRS oximeters using the developed CVM.

Main Methods:

  • A 3D-printed cerebrovascular module (CVM) with 148 channels was developed and characterized using imaging and spectrophotometry.
  • The CVM was filled with bovine blood (30-90% oxygen saturation) and encased in silicone layers to simulate extracerebral tissues.
  • Two commercial NIRS cerebral oximeters were tested for saturation measurement accuracy and precision.

Main Results:

  • One NIRS oximeter demonstrated high precision but accuracy varied with saturation and simulated tissue depth.
  • The second NIRS oximeter showed lower precision but was more robust to variations in simulated extracerebral tissues.
  • The 3D-printed CVM proved effective in assessing NIRS oximeter performance under controlled conditions.

Conclusions:

  • 3D-printed channel array phantoms, like the CVM, offer a promising, standardized approach for evaluating NIRS cerebral oximeter performance.
  • This phantom technology can help address the accuracy discrepancies observed in commercial NIRS systems.
  • Standardized testing is crucial for ensuring reliable real-time surgical monitoring with cerebral oximetry.