Two synchronous lung metastases from malignant melanoma: the same patient but different morphological patterns

Area of Science:

• Oncology
• Radiology
• Pathology

Background:

• Malignant melanoma is an aggressive cancer known for its high metastatic potential.
• Pulmonary metastases are common in malignant melanoma, typically appearing as solid nodules on CT scans.

Observation:

• This report details an unusual case of malignant melanoma with two synchronous pulmonary metastases.
• These metastases exhibited distinct characteristics: one solid nodule and one subsolid nodule.
• The nodules differed in density on CT imaging and morphology on histologic examination.

Findings:

• The study presents a rare instance of synchronous pulmonary metastases from malignant melanoma with dual presentations (solid and subsolid).
• It provides a radiologic-pathologic correlation for these two distinct patterns of metastatic disease in the lung.

Implications:

• This case expands the understanding of the varied presentations of pulmonary metastases in malignant melanoma.
• It underscores the importance of considering diverse imaging findings in diagnosing melanoma lung metastases.
• The radiologic-pathologic correlation aids in accurate interpretation and management of such cases.