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Published on: September 22, 2023
Restless legs syndrome in children with allergic rhinitis: A comparative study on frequency, severity and sleep
Meral Bilgilisoy Filiz1, Serkan Filiz2, Rıza Taner Baran3
1Department of Physical Medicine and Rehabilitation, Health Sciences University, Antalya Training and Research Hospital, Antalya, Turkey.
Insights
Restless Legs Syndrome (RLS) was more severe, not more frequent, in children with allergic rhinitis (AR). This study found no significant impact of RLS on sleep quality in pediatric AR patients.
Area of Science:
- Pediatric Allergy and Immunology
- Sleep Medicine
- Neurology
Background:
- Allergic rhinitis (AR) is common in children and can disrupt sleep.
- Restless Legs Syndrome (RLS) is a neurological disorder characterized by an urge to move the legs, often affecting sleep.
Purpose of the Study:
- To investigate the frequency and severity of RLS in children with AR.
- To examine the relationship between RLS and sleep quality in pediatric AR patients.
- To test the hypothesis that RLS contributes to sleep disturbances in children with AR.
Main Methods:
- 143 children with AR and 144 healthy controls (aged 8-18) were assessed.
- AR diagnosis followed established guidelines; RLS was diagnosed using International RLS study group (IRLSSG) criteria.
- RLS severity and sleep quality were measured using IRLSSG rating scale and Pittsburgh Sleep Quality Index (PSQI), respectively.
Main Results:
- RLS occurred in 9.1% of AR patients and 4.2% of controls (p=0.159).
- RLS severity scores were significantly higher in the AR group (p=0.046).
- No significant differences in sleep quality (PSQI scores) were found between groups or between AR patients with and without RLS.
Conclusions:
- Children with AR exhibit more severe RLS, although not a higher frequency compared to controls.
- RLS does not appear to significantly impact overall sleep quality in children with AR.
- Further research may be needed to understand the complex interplay between AR, RLS, and sleep in children.
Objectives:
This study aims to investigate the frequency and severity of restless legs syndrome (RLS) and its relationship with sleep quality in children with allergic rhinitis (AR) with the hypothesis that comorbid RLS may be an additional causative factor of sleep disturbances in pediatric AR.
Patients And Methods:
A total of 143 children with AR (aged 8-18 years) and 144 healthy control subjects (aged 8-18 years) were included. The diagnosis of AR was established on history, clinical examination and skin prick test according to the Allergic Rhinitis and its Impact on Asthma guidelines. Presence of RLS was determined using the International RLS study group (IRLSSG) criteria. The severity of RLS was assessed using the IRLSSG rating scale. Sleep quality was evaluated by Pittsburgh Sleep Quality Index (PSQI).
Results:
Thirteen patients (9.1%) in AR group, and six children (4.2%) in control group had RLS (p=0.159). The frequency of RLS in AR group was higher than two folds when compared to the control group; however, the difference was not statistically significant. Restless legs syndrome severity score was significantly higher in AR group than control group (15.00 [11-20] and 11.00 [10-16] respectively, p=0.046). Total PSQI scores were similar between groups. Also, no significant differences were observed in total PSQI scores of AR patients with or without RLS.
Conclusion:
Restless legs syndrome was not more common but was more severe in children with AR. There was no evidence that RLS has an obvious effect on sleep quality in children with AR.
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