A versatile and accessible polymer coating for functionalizable zwitterionic quantum dots with high DNA grafting efficiency
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Updated: Jan 20, 2026

Production and Targeting of Monovalent Quantum Dots
Published on: October 23, 2014
Chloé Grazon1, Margaret Chern2, Katherine Ward3
1Univ. Bordeaux, CNRS, Bordeaux INP, LCPO, UMR 5629, F-33600, Pessac, France and Department of Chemistry, Boston University, Boston, MA, USA.
Abstract:
Efficient and versatile functionalization of poly(anhydride maleic-alt-isobutylene) (PIMA), with economical commercial reagents, results in the one-step/one-day production of a copper-free click chemistry-ready carboxybetaine-like coating for quantum dots (QDs). The QDs are bright and stable in aqueous media and easily grafted with DNA with >95% efficiency.
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Dot Product
In engineering, the dot product of any two vectors is the product of the magnitudes of the vectors and the cosine of the angle between them. It is denoted by a dot symbol between the two vectors.
Consider a vehicle pulling an object along the ground using a rope. If the rope makes an angle with the horizontal axis, the work done can be calculated using the dot product of the force applied and the object's displacement.
The dot...

