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Construction of a novel DNA-based comparator and its application in intelligent analysis
Dan Huang1, Chen Guo1, Jiarong Miao1
1College of Chemistry, Sichuan University, Chengdu 610064, Sichuan, China. yangqf@scu.edu.cn.
Abstract:
In this work, a novel and general comparator was constructed based on cascaded strand displacement reactions and DNA hybridization and its potential in intelligently weighing the quantitative predominance of two targets was explored in a complex biological matrix, which not only enriches the information processing mode of DNA computation but also provides an instructive way to deal with quantitative analyzing tasks in further DNA-based logic sensors.
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