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Author Spotlight: Enhancing Coronary Artery Revascularization
Published on: September 15, 2023
Early Outcomes of Low Postoperative Bleeding after Off-Pump Coronary Artery Bypass Grafting
Weitie Wang1, Yong Wang1, Hulin Piao1
1Jilin University 2nd Hospital of Bethune Department of Cardiovascular Surgery Changchun Jilin China Department of Cardiovascular Surgery, 2nd Hospital of Bethune, Jilin University, Changchun, Jilin, China.
Insights
Low postoperative bleeding in off-pump coronary artery bypass grafting (CABG) patients is linked to shorter ventilation times and better hemodynamic stability. This finding suggests improved early outcomes without increasing infection or ICU stay.
Area of Science:
- Cardiovascular Surgery
- Anesthesiology
- Critical Care Medicine
Background:
- Off-pump coronary artery bypass grafting (CABG) is a surgical procedure to improve blood flow to the heart.
- Postoperative bleeding is a common complication that can impact patient outcomes.
- Understanding the influence of bleeding volume on early recovery is crucial for optimizing patient care.
Purpose of the Study:
- To investigate the relationship between low postoperative bleeding and early outcomes in patients undergoing off-pump CABG.
- To determine if reduced bleeding volume correlates with improved patient recovery metrics.
Main Methods:
- Retrospective analysis of ischemic heart disease patients who underwent off-pump CABG between January 2013 and December 2017.
- Patients were categorized into low-bleeding (<300 ml/12h) and bleeding (≥300 ml/12h) groups based on chest tube drainage.
- Comparison of clinical characteristics and early postoperative outcomes between the two groups.
Main Results:
- The low-bleeding group exhibited significantly shorter mechanical ventilation times (6.86±3.78 h vs. 10.66±5.19 h) and more stable hemodynamics.
- Lower rates of vasoactive agent use were observed in the low-bleeding group.
- No significant differences were found in reoperation for bleeding, ICU stay, or hospital stay between groups.
Conclusions:
- Postoperative bleeding less than 300 ml/12h in off-pump CABG patients is not associated with increased need for blood transfusion or reoperation.
- Reduced bleeding volume (<300 ml/12h) contributes to decreased mechanical ventilation time and enhanced hemodynamic stability.
- Bleeding volumes up to 800 ml/12h did not negatively impact infection rates or ICU length of stay.
Objective:
To investigate whether low bleeding influences the early outcomes after off-pump coronary artery bypass grafting (CABG).
Methods:
Retrospective analysis of ischemic heart disease patients who underwent off-pump CABG from January 2013 to December 2017. Patients were divided into low-bleeding group (n=659) and bleeding group (n=270), according to total drainage from chest tube during the first postoperative 12 hours. Clinical material and early outcomes were compared between the groups.
Results:
Baseline was similar in the two groups. Operation time was 270±51 min in the low-bleeding group and 235±46 min in the bleeding group (P<0.0001). The low-bleeding group presented smaller drainage during the first 12 h (237±47 ml) and shorter mechanical ventilation time (6.86±3.78 h) than the bleeding group (557±169 ml and 10.66±5.19 h, respectively) (P<0.0001). Hemodynamic status was more stable in the low-bleeding group (P<0.0001) and usage rate of more than two vasoactive agents in this group was lower than in the bleeding group (P<0.0001). Number of distal anastomosis, reoperation for bleeding, suddenly increase in chest tube output, intensive care unit (ICU) stay, hospital stay, and other early outcomes had no statistical significance between the groups (P>0.05).
Conclusion:
Postoperative bleeding < 300 ml/12 h in off-pump CABG patients did not require blood product transfusion and reoperation and that would contribute to reduction in mechanical ventilation time and maintaining hemodynamic stability. Bleeding < 800 ml during the first postoperative 12 h did not increase infection rates and ICU length of stay.
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