Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Trial and Error and Algorithm01:12

Trial and Error and Algorithm

398
A problem-solving strategy is a plan of action used to find a solution. Different strategies have distinct action plans. Trial and error involves trying different solutions until one works. For instance, to fix a broken printer, you might check ink levels, ensure the paper tray isn't jammed, and verify the printer's connection to your laptop. This method can be time-consuming but is commonly used. Thomas Edison, for example, used trial and error to find a suitable filament for the light...
398
Adaptability of Cytoskeletal Filaments01:12

Adaptability of Cytoskeletal Filaments

5.7K
The cytoskeleton is a complex dynamic structure performing varied functions based on cellular requirements. The adaptability of the individual filaments in the cytoskeleton determines their ability to perform various functions within the cell. It can undergo rapid reorganization during processes like cell division or remain stable for several hours as in the interphase. The adaptability of these filaments depends on stringent regulatory mechanisms. The microfilament and microtubules of the...
5.7K
Natural Selection and Adaptation01:15

Natural Selection and Adaptation

1.2K
Natural selection, a fundamental concept in evolutionary biology, is the mechanism by which evolution is driven, favoring organisms that are best adapted to their environments. This process enhances their chances of survival and reproduction. Adaptation, a key outcome of this process, involves genetic modifications that optimize an organism's functionality under specific environmental challenges, such as extreme cold or thinner air at high altitudes.
Beyond physical adaptations,...
1.2K
Introduction to Innate and Adaptive Immunity01:21

Introduction to Innate and Adaptive Immunity

9.0K
The human immune system is a complex defense mechanism that protects the body from harmful pathogens and foreign substances. It comprises two crucial components: innate and adaptive immunity.
Innate immunity is the body's natural, nonspecific defense system that acts quickly to protect against pathogens. It incorporates physical barriers like skin and mucous membranes and cellular elements such as phagocytes and natural killer cells. This part of our immune system provides an immediate,...
9.0K
Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving01:29

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving

295
Mechanistic models play a crucial role in algorithms for numerical problem-solving, particularly in nonlinear mixed effects modeling (NMEM). These models aim to minimize specific objective functions by evaluating various parameter estimates, leading to the development of systematic algorithms. In some cases, linearization techniques approximate the model using linear equations.
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
295
Microtubule Associated Proteins (MAPs)01:42

Microtubule Associated Proteins (MAPs)

5.8K
Microtubule function and architecture are regulated by an array of specialized proteins called microtubule-associated proteins or MAPs. These proteins are widespread across different organisms and have conserved protein motifs, like the multi-TOG domain for tubulin binding found in the CLASP family of MAPs. Some MAPs are lineage-specific based on their conserved domains. Their functions depend upon the cytoskeletal architecture and cell type they are located within. In-plant cells, a specific...
5.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cardiac magnetic resonance imaging parameters predict new-onset symptoms of heart failure in hypertrophic cardiomyopathy.

ESC heart failure·2026
Same author

Generative artificial intelligence for inpatient documentation summarization: mixed-methods quality assessment and early real-world experience.

Journal of the American Medical Informatics Association : JAMIA·2026
Same author

Artificial intelligence for predicting hospital admissions from the emergency department: a prospective, quasi-experimental study.

Nature communications·2026
Same author

Hospital-Based Shootings in the US, 2000-2024: A Systematic Review.

JAMA network open·2026
Same author

New world screwworm: A focused review for the emergency medicine clinician.

The American journal of emergency medicine·2026
Same author

Clinical validation of an AI-based blood testing device for diagnosis and prognosis of acute infection and sepsis.

Nature medicine·2025
Same journal

sEEGnal: an automated EEG preprocessing pipeline evaluated against expert-driven preprocessing.

Computers in biology and medicine·2026
Same journal

Corrigendum to "Integrating experimental biology, computational methods, and artificial Intelligence in anticancer drug discovery: Bridging the translational Gap" [Comput. Biol. Med. 213 (2026) 111832].

Computers in biology and medicine·2026
Same journal

Organ dose optimization for a point-of-care forearm X-ray photon-counting CT.

Computers in biology and medicine·2026
Same journal

Physics-guided transformation of breathomic feature spaces into disease-specific representations for respiratory disease classification.

Computers in biology and medicine·2026
Same journal

An AI-driven deep learning pipeline for taxonomic classification and biodiversity assessment of deep-sea environmental DNA.

Computers in biology and medicine·2026
Same journal

Rapid personalisation of cardiovascular models using invasively measured right ventricular pressure.

Computers in biology and medicine·2026
See all related articles

Related Experiment Video

Updated: Jan 20, 2026

Preparation of Complaint Matrices for Quantifying Cellular Contraction
11:38

Preparation of Complaint Matrices for Quantifying Cellular Contraction

Published on: December 14, 2010

18.3K

CCMapper: An adaptive NLP-based free-text chief complaint mapping algorithm.

Mohammad Samie Tootooni1, Kalyan S Pasupathy2, Heather A Heaton3

  • 1Department of Health Informatics and Data Science, Loyola University Chicago, Maywood, IL, USA; Center for Health Outcomes and Informatics Research, Loyola University Chicago, Maywood, IL, USA.

Computers in Biology and Medicine
|August 28, 2019
PubMed
Summary
This summary is machine-generated.

A new algorithm, Chief Complaint Mapper (CCMapper), automatically categorizes emergency department (ED) chief complaints (CCs) with high accuracy. This tool simplifies data processing and supports clinical decision-making in EDs.

Keywords:
Emergency departmentFree-text chief complaintsHeuristicHuman consensus-based validationIterative enhancementMapping algorithmNatural language processing

More Related Videos

Area-based Image Analysis Algorithm for Quantification of Macrophage-fibroblast Cocultures
07:05

Area-based Image Analysis Algorithm for Quantification of Macrophage-fibroblast Cocultures

Published on: February 15, 2022

2.9K
X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging
08:30

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

Published on: September 11, 2011

14.8K

Related Experiment Videos

Last Updated: Jan 20, 2026

Preparation of Complaint Matrices for Quantifying Cellular Contraction
11:38

Preparation of Complaint Matrices for Quantifying Cellular Contraction

Published on: December 14, 2010

18.3K
Area-based Image Analysis Algorithm for Quantification of Macrophage-fibroblast Cocultures
07:05

Area-based Image Analysis Algorithm for Quantification of Macrophage-fibroblast Cocultures

Published on: February 15, 2022

2.9K
X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging
08:30

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

Published on: September 11, 2011

14.8K

Area of Science:

  • Emergency Medicine
  • Natural Language Processing
  • Health Informatics

Background:

  • Chief complaints (CCs) are crucial initial data in emergency departments (EDs).
  • Manual categorization of free-text CCs is time-consuming and prone to errors.
  • Standardizing CC data is essential for clinical decision support and research.

Purpose of the Study:

  • To develop and validate a heuristic methodology for automatically mapping free-text chief complaints (CCs) into a structured list.
  • To create a natural language processing-based algorithm, CCMapper, for efficient and accurate CC categorization.
  • To assess the performance of CCMapper in a real-world ED setting.

Main Methods:

  • A comprehensive structured list of CCs was created by experienced Emergency Medicine (EM) physicians.
  • A natural language processing (NLP) algorithm, CCMapper, was developed using this structured list.
  • CCMapper was trained and validated on free-text CC data from the Mayo Clinic ED, employing a consensus-based validation approach.

Main Results:

  • High inter-physician agreement (κ = 0.958) with minimal human error (<2%) was achieved during manual mapping.
  • CCMapper demonstrated high performance on the validation set: 94.2% sensitivity, 99.8% specificity, and 94.7% F-score.
  • For multi-CC entries, CCMapper achieved 82.3% sensitivity, 99.1% specificity, and an 82.3% F-score.

Conclusions:

  • CCMapper offers a simple, high-performing solution for automatically categorizing ED chief complaints.
  • The algorithm's ability to incorporate new data facilitates its adoption by other EDs for improved clinical decision-making.
  • CCMapper can aid in developing predictive models for critical ED events, such as ICU admissions.