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Related Experiment Videos

Lupus enteritis masquerading as Crohn's disease.

Xiu-Li Zhu1, Xue-Mei Xu2, Si Chen2

  • 1Department of Gastroenterology, Anhui Provincial Hospital, Hefei, Anhui, 230001, People's Republic of China. 1216243099@qq.com.

BMC Gastroenterology
|August 29, 2019
PubMed
Summary

Lupus enteritis, a rare complication of systemic lupus erythematosus (SLE), can mimic Crohn's disease (CD) on imaging and histology. This case highlights the nonspecific endoscopic findings of lupus enteritis.

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Area of Science:

  • Gastroenterology
  • Rheumatology
  • Internal Medicine

Background:

  • Systemic lupus erythematosus (SLE) is a multi-organ autoimmune disease with significant morbidity and mortality.
  • Lupus enteritis, a rare SLE complication, involves intestinal vasculitis but often presents with nonspecific mucosal changes.
  • Crohn's disease (CD) is a chronic gastrointestinal inflammatory disorder diagnosed via clinical, endoscopic, histological, and radiological evaluation.

Observation:

  • A rare case of lupus enteritis in a 71-year-old male is presented.
  • The patient's lupus enteritis exhibited similarities to CD in endoscopic, histological, and radiological findings.
  • No prior reported cases of lupus enteritis with these specific characteristics exist.

Findings:

  • Endoscopic examination of lupus enteritis revealed nonspecific features.
Keywords:
Crohn’s diseaseLupus enteritisSystemic lupus erythematosus

Related Experiment Videos

  • Key endoscopic descriptors for lupus enteritis in this case included spaciousness, cleanliness, and absence of moss ulcers.
  • The gastrointestinal tract involvement was discontinuous.

    • Implications:

    • The nonspecific nature of lupus enteritis necessitates careful differential diagnosis, especially when symptoms overlap with Crohn's disease.
    • Accurate diagnosis of lupus enteritis is crucial for appropriate management and improved patient outcomes.
    • This case expands the understanding of lupus enteritis's varied clinical and endoscopic presentations.