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Outcomes after Surgical Resection of Hilar Cholangiocarcinoma

Faisal Saud Dar1, Muhammad Atiq1, Neelam Shahzadi1

  • 1Department of BPB Surgery and Liver Transplant, Shifa International Hospital, Islamabad, Pakistan.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|August 29, 2019
PubMed

Insights

Surgical resection of hilar cholangiocarcinoma (hCCA) is complex. Experienced centers can achieve outcomes comparable to international standards, with 5-year survival rates of 60% recurrence-free and 39% overall.

Area of Science:

  • Hepatobiliary Surgery
  • Surgical Oncology
  • Gastroenterology

Background:

  • Hilar cholangiocarcinoma (hCCA) presents significant surgical challenges.
  • Long-term outcomes following hCCA resection are crucial for patient management.

Purpose of the Study:

  • To report the long-term outcomes after surgical resection of hilar cholangiocarcinoma (hCCA).

Main Methods:

  • A cohort study involving 24 patients who underwent surgical resection for hCCA.
  • Outcomes assessed included 90-day morbidity and mortality, 5-year recurrence-free survival (RFS), and overall survival (OS).

Main Results:

  • The 90-day mortality rate was 4.1%, with 66.7% experiencing morbidity.
  • The 5-year recurrence-free survival (RFS) was 60%, and overall survival (OS) was 39%.
  • Surgical procedures included various hepatectomy types, with some requiring portal vein resection.

Conclusions:

  • Surgical resection of hCCA is technically demanding.
  • Achieving outcomes comparable to international standards is feasible in experienced centers.
Abstract

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