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Area of Science:

  • Critical care medicine
  • Trauma surgery
  • Nutritional science

Background:

  • Polytrauma patients face significant malnutrition risks due to metabolic trauma response.
  • Limited understanding exists regarding malnutrition prevalence and consequences in these patients.
  • Early identification of malnourished polytrauma patients is vital for preventing complications and improving outcomes.

Purpose of the Study:

  • To determine if malnutrition in ICU polytrauma patients correlates with higher complication rates.
  • To assess the prevalence of pre-existing and hospital-acquired malnutrition.
  • To evaluate malnutrition's association with long-term outcomes and serum biomarkers.

Main Methods:

  • International prospective observational cohort study across five Level-1 trauma centers.
  • Inclusion of adult polytrauma patients (Injury Severity Score ≥16) admitted directly to the ICU.
  • Assessment of nutritional status using Subjective Global Assessment (SGA) and Nutritional Risk in Critically Ill (NUTRIC) score.

Main Results:

  • Daily collection of nutritional intake, biomarkers (albumin, pre-albumin), and complications.
  • Follow-up to one year post-discharge for long-term outcome assessment.
  • Analysis of the relationship between malnutrition and clinical outcomes in polytrauma patients.

Conclusions:

  • This study will provide crucial insights into the impact of malnutrition on polytrauma patients in the ICU.
  • Findings aim to inform clinical practice for better nutritional management and patient recovery.