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Author Spotlight: Exploring Cellular Zinc Regulation Through ZnT1 Functionality
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BIOAVAILABILITY OF BIOTRANSFORMED ZINC ENRICHED DAHI IN WISTAR RATS.

Jagan Mohan1, Syed Azmal Ali2, Ranvir Suvartan3

  • 1National Collection of Dairy Cultures (NCDC) Lab, Dairy Microbiology Division.

International Journal of Probiotics & Prebiotics
|August 29, 2019
PubMed
Summary

Organic zinc in dahi (fermented milk) shows higher bioavailability in rats compared to inorganic zinc sulfate. This zinc-enriched dahi significantly improved body weight and zinc levels in tissues.

Keywords:
BioavailabilityDahiLABMicronutrient deficiencyProbioticZinc

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Area of Science:

  • Nutritional Science
  • Biochemistry
  • Food Science

Background:

  • Dietary zinc is crucial for numerous physiological functions.
  • Bioavailability of zinc from different food sources varies significantly.
  • Organic zinc forms are often proposed to have better absorption rates than inorganic forms.

Purpose of the Study:

  • To investigate the in vivo bioavailability of biotransformed organic zinc from zinc-enriched dahi (ZED) and zinc-enriched probiotic dahi (ZEP).
  • To compare the absorption and distribution of organic zinc from dahi with inorganic zinc sulfate.

Main Methods:

  • Animal study using rats divided into groups fed basal diet, inorganic zinc sulfate, ZED, or ZEP.
  • Body weight and food intake were monitored over three weeks.
  • Zinc content in serum, femur bone, liver, and hair was analyzed using Atomic Absorption Spectroscopy (AAS).
  • Zinc excretion in feces was quantified.

Main Results:

  • Rats fed ZED and ZEP showed significantly increased body weight and food intake (p<0.001).
  • Significantly higher zinc concentrations (p<0.001) were found in the serum, femur bone, liver, and hair of rats consuming ZED/ZEP.
  • Rats fed the basal diet or inorganic zinc sulfate excreted larger amounts of zinc in their feces.

Conclusions:

  • Biotransformed organic zinc in dahi exhibits high bioavailability in vivo.
  • Organic zinc from dahi is more effectively absorbed and retained compared to inorganic zinc sulfate.
  • Zinc-enriched dahi represents a promising functional food for improving zinc status.