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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Angle Closure Glaucoma: Treatment01:28

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Hormones can be classified into three main types based on their chemical structures: steroids, peptides, and amines. Their actions are mediated by the specific receptors they bind to on target cells.
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Related Experiment Video

Updated: Jan 20, 2026

Ultrasound Cyclo Plasty in Eyes with Glaucoma
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Ex-PRESS implantation for different types of glaucoma.

Meltem Guzin Altinel1, Ayse Yagmur Kanra2, Remzi Karadag3

  • 1Department of Ophthalmology, Fatih Sultan Mehmet Training and Research Hospital, Icerenkoy Atasehir 34752, Istanbul, Turkey.

International Journal of Ophthalmology
|August 29, 2019
PubMed
Summary

The Ex-PRESS P200 glaucoma shunt effectively lowers intraocular pressure (IOP) and reduces medication needs in medically uncontrolled glaucoma patients. This surgical option offers significant IOP reduction and improved outcomes for difficult-to-manage glaucoma.

Keywords:
Ex-PRESS implantglaucomaglaucoma surgery

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Area of Science:

  • Ophthalmology
  • Glaucoma Surgery
  • Medical Devices

Background:

  • Medically uncontrolled glaucoma presents a significant challenge in maintaining ocular health.
  • The Ex-PRESS P200 glaucoma shunt is a device designed to manage intraocular pressure (IOP).

Purpose of the Study:

  • To evaluate the clinical outcomes, efficacy, and safety of the Ex-PRESS P200 glaucoma shunt.
  • To assess the device's performance in patients with various types of medically uncontrolled glaucoma.

Main Methods:

  • Retrospective analysis of 31 eyes with medically uncontrolled glaucoma treated with Ex-PRESS P200 shunt implantation.
  • Evaluation of preoperative and postoperative intraocular pressure (IOP), medication use, and complications.

Main Results:

  • Significant reduction in mean IOP from 28.7±10.3 mm Hg to 15.3±5.2 mm Hg (39.9% decrease).
  • Average number of antiglaucomatous drugs reduced from 3.9 to 1.7 postoperatively.
  • Complete success rate of 32.3% and qualified success rate of 77.5% observed.

Conclusions:

  • Ex-PRESS P200 glaucoma shunt implantation is an effective surgical option for medically uncontrolled glaucoma.
  • The procedure leads to significant IOP reduction and decreased reliance on antiglaucomatous medications.