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Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
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Devices in Heart Failure Patients-Who Benefits From ICD and CRT?

Alexander Breitenstein1, Jan Steffel1

  • 1Electrophysiology, Department of Cardiology, University Hospital Zurich, Zurich, Switzerland.

Frontiers in Cardiovascular Medicine
|August 29, 2019
PubMed

Insights

Heart failure treatment advances are ongoing, but ventricular arrhythmias remain a concern. Implantable cardioverter defibrillators (ICDs) and cardiac resynchronization therapy (CRT) reduce sudden death but are underutilized.

Area of Science:

  • Cardiology
  • Medical Devices
  • Heart Failure Management

Background:

  • Heart failure (HF) presents significant morbidity and mortality.
  • Sudden cardiac death in HF patients is often caused by ventricular arrhythmias.
  • Current treatments, including implantable cardioverter defibrillators (ICDs) and cardiac resynchronization therapy (CRT), are effective but underutilized.

Purpose of the Study:

  • To review the current landscape of device therapy for heart failure.
  • To highlight the underutilization of ICDs and CRT.
  • To provide an outlook on future device innovations in HF management.

Main Methods:

  • Literature review of randomized trials and clinical guidelines.
  • Analysis of current trends in device implantation for heart failure.
  • Discussion of emerging technologies in cardiac electrophysiology.

Main Results:

  • ICDs and CRT significantly reduce mortality from arrhythmic sudden death in selected HF patients.
  • Despite proven efficacy, ICD and CRT utilization rates remain suboptimal globally.
  • Upcoming device novelties promise enhanced therapeutic options for HF patients.

Conclusions:

  • Optimizing the use of existing ICD and CRT therapies is crucial for improving outcomes in heart failure.
  • Addressing barriers to device utilization is essential.
  • Future technological advancements hold promise for further improving the management of heart failure and preventing sudden cardiac death.

Keywords:
cardiac resynchronizationheart failureimagingimplantable cardioverter defibrillatorsubcutaneous ICD (S-ICD)

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