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Updated: Jan 20, 2026

Synthesis and Performance Characterizations of Transition Metal Single Atom Catalyst for Electrochemical CO2 Reduction
Published on: April 10, 2018
Transition-Metal Catalyst Free Oxidative Radical Arylation of N-Methylpyrrole
Esma Kocaoğlu1, Muhammed A Karaman1, Hatun Tokgöz1
1Department of Chemistry, Kamil Özdağ Science Faculty, Karamanoğlu Mehmetbey University, 70100 Karaman, Turkey.
Abstract:
This study represents an expansion of the application of catalysis in air through conventional coupling and free radical processes. A reactive free aryl radical intermediate was generated via the oxidation of an activated Ar-NH-NH2 bond by air as a simple and readily available oxidant. For this purpose, the usability of phenylhydrazine and phenylhydrazine hydrochloride salt reagents for the direct arylation of pyrrole with aryl radicals was investigated. The facile coupling of N-methylpyrrole with aryl radicals was easily applied for the convenient direct synthesis of C-2 arylated pyrroles without a transition-metal catalyst.
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