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Updated: Jan 20, 2026
Optical Trapping of Plasmonic Nanoparticles for In Situ Surface-Enhanced Raman Spectroscopy Characterizations
Published on: June 23, 2022
Searching the Theoretical Ultimate Limits of Probing Surface-Enhanced Raman Optical Activity
Li Hu1,2, Feng Xi2, Linhong Qv1
1Key Laboratory of Materials Modification by Laser, Electron, and Ion Beams (Ministry of Education), School of Physics, Dalian University of Technology, Dalian 116024, P. R. China.
Abstract:
The single-molecule Raman detection has been realized for a long time because of the enhancement effect of surface plasmons. However, the small cross section of Raman optical activity (ROA) makes it so hard to detect the ROA of even a few molecules; and a normal surface-enhanced ROA (SE-ROA) is also very time consumable even with strong laser power. Detecting ROA in an economic way is an important issue. In this paper, we discuss the ultimate limit of the SE-ROA and provide the enhancement factor formula for SE-ROA. Following the formula, we proposed a structure with both huge Raman enhancement and ROA enhancement, which is helpful for single-molecule ROA detection.
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