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Updated: Jan 20, 2026
Author Spotlight: Single-Molecule Surface-Enhanced Raman Scattering Measurements Enabled by Plasmonic DNA Origami Nanoantennas
Published on: July 21, 2023
Synthesis of Spiked Plasmonic Nanorods with an Interior Nanogap for Quantitative Surface-Enhanced Raman Scattering
Yang Zhang1, Chen Li2, Zahra Fakhraai2
1Smart Hybrid Materials (SHMs) Laboratory, Advanced Membranes and Porous Materials Center, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Kingdom of Saudi Arabia.
Abstract:
Realizing quantitative surface-enhanced Raman scattering (SERS) analysis is extremely helpful and challenging. Here, we utilize a facile method to synthesize spiked plasmonic nanorods with an interior gap. The Raman signal from the molecules embedded in the gap can be dramatically enhanced, leading to strong, stable, and reproducible SERS signals that can be used as an internal reference for quantitative SERS analysis. We demonstrate that the rough exterior surface has a good performance in enhancing the Raman signal of polycyclic aromatic hydrocarbon molecules adsorbed on the surface. The result shows that this method is applicable for a large range of analyte concentrations and there is an excellent linear relationship between the SERS intensity ratio and the analyte concentration (0.5-100 μM).
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