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Updated: Jan 20, 2026
Oxidation Numbers and Rules for Assigning Oxidation Numbers
Selective Oxidation of 5-(Hydroxymethyl)furfural to DFF Using Water as Solvent and Oxygen as Oxidant with
Francesco Nocito1, Maria Ventura2, Michele Aresta3
1Department of Chemistry, University of Bari, Campus Universitario, 70126 Bari, Italy.
Abstract:
5-Hydroxymethylfurfural (5-HMF) can be considered a prominent building block: because of the presence of the alcohol and aldehyde moieties, it can be used to generate useful molecules as chemicals of industrial interest with high added value, monomers for polymers, and even fuels. This article shows how building up mixed oxides of different complexities and properties may drive the selectivity toward one of the possible products generated from 5-HMF. In particular, mixed oxides based on cerium and other metals abundant on the earth-crust perform the selective oxidation of 5-HMF to 2,5-diformylfuran (94%), using oxygen as oxidant and water as solvent. The roles of the reaction conditions (temperature, reaction time, oxygen pressure, concentration of the substrate), the chemical composition, the acidic/basic properties, and redox properties of the catalysts are discussed.
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