Related Experiment Video
Updated: Jan 20, 2026

Cardiac Magnetic Resonance Imaging at 7 Tesla
Published on: January 6, 2019
C-H Imidation of 7-Deazapurines
Nazarii Sabat1,2, Lenka Poštová Slavětínská2, Blanka Klepetářová2
1Department of Organic Chemistry, Faculty of Science, Charles University in Prague, Hlavova 8, 12843 Prague-2, Czech Republic.
Abstract:
We developed and presented here a ferrocene-catalyzed C-H imidation of 7-deazapurines (pyrrolo[2,3-d]pyrimidines) with N-imidyl peroxyesters. The reactions occur regioselectively at position 8 in 7-deazapurines, leading to a series of 8-succinimido-, phtalimido-, or naphthalimido-7-deazapurine derivatives. Attempted hydrazinolysis of resulting 8-imidyl-7-deazapurines led to corresponding 8-amino-7-deazapurine, which was very unstable and quickly decomposed.
Related Concept Videos
09:14Cardiac Magnetic Resonance Imaging at 7 Tesla
02:54Caspase-3/7 Assay: A Luminescence-Based Assay to Quantify Apoptosis by Measuring Caspase-3/7 Activities in Frog Skin Explants
04:06Identification of Pre-weanling 7-Day-Old Mice with Pinna Edge Biopsies
11:13Exploring the Pharmacological Action and Molecular Mechanism of Salidroside in Inhibiting MCF-7 Cell Proliferation and Migration
05:13Quantifying the Level of 8-oxo-dG Using ELISA Assay to Evaluate Oxidative DNA Damage in MCF-7 Cells
08:38Electrospray Deposition of Uniform Thickness Ge23Sb7S70 and As40S60 Chalcogenide Glass Films

