Related Experiment Video
Updated: Jan 20, 2026
Sample Preparation for Probe Electrospray Ionization Mass Spectrometry
Published on: February 19, 2020
Improving the Performance of the Mini 2000 Mass Spectrometer with a Triboelectric Nanogenerator Electrospray
Jianli Liu1, Wei Tang2, Xiangzhi Meng1
1School of Life Science, Beijing Institute of Technology, Beijing 100081, China.
Abstract:
Balancing the contradiction between portability and analytical performances of a miniaturized mass spectrometer is vital to extend its on-site applications. In this study, triboelectric nanogenerator (TENG)-driven ion sources were coupled with our home-built Mini 2000 system and applied to the analyses of different samples. Compared with the conventional direct current (DC) nanoelectrospray ionization (nanoESI) source, the ion intensity of the TENG-nanoESI miniature mass spectrometer was improved by ∼3 times. Moreover, maybe due to the different pathways of ion formation in comparison with DC electrospray, TENG electrospray is shown to reduce the salt suppression effect during ionization. With these figures of merit, the direct detection of reserpine in saliva was demonstrated using the TENG-Mini 2000 system.
Related Concept Videos
05:47Sample Preparation for Probe Electrospray Ionization Mass Spectrometry
08:43A Quantitative Assessment of The Yeast Lipidome using Electrospray Ionization Mass Spectrometry
06:21Imaging of Biological Tissues by Desorption Electrospray Ionization Mass Spectrometry
08:23Real-time Breath Analysis by Using Secondary Nanoelectrospray Ionization Coupled to High Resolution Mass Spectrometry
10:47Whole-body Mass Spectrometry Imaging by Infrared Matrix-assisted Laser Desorption Electrospray Ionization (IR-MALDESI)
12:59A Study of the Complexation of Mercury(II) with Dicysteinyl Tetrapeptides by Electrospray Ionization Mass Spectrometry