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Deleterious Substances in Aggregate01:25

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Deleterious substances in aggregates can be detrimental to the quality and durability of concrete. These substances include organic impurities like loam, which interfere with cement hydration and are usually present in the sand. These prevent a good bond between aggregate and cement paste. Organic impurities can be detected using the colorimetric test, where the darkness of a solution after agitation indicates the level of organic content.
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Substance-Based Bibliometrics: Identifying Research Gaps by Counting and Analyzing Substances.

Robert Tomaszewski1

  • 1California State University, Fullerton, 800 North State College Blvd, Fullerton, California 92831 United States.

ACS Omega
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This study introduces substance-based bibliometrics to identify research gaps in chemical sciences. By analyzing substance occurrences and bioactivity, it aids in drug discovery and expanding scientific knowledge.

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Area of Science:

  • Bibliometrics
  • Chemical Informatics
  • Drug Discovery

Background:

  • Identifying research gaps is crucial for scientific writing and grant proposals.
  • Substance-based bibliometrics offers a novel approach to assess chemical information.
  • Linking chemical substances to bioactivity can reveal insights for drug design.

Purpose of the Study:

  • To explore the use of substance-based bibliometrics for identifying research gaps.
  • To develop strategies for discovering new research ideas in the chemical sciences.
  • To assess the relevance of chemical substances in biochemical, biological, and medicinal contexts.

Main Methods:

  • Utilizing Chemical Abstracts via the SciFinder database for substance occurrence counts.
  • Implementing search strategies to identify potential research gaps.
  • Visualizing chemical structures alongside known bioactivity and target indicators.

Main Results:

  • Demonstrated a method for quantifying substance prevalence in scientific literature.
  • Identified potential avenues for research gap discovery through bibliometric analysis.
  • Provided a framework for linking chemical structures to their biological relevance.

Conclusions:

  • Substance-based bibliometrics is a valuable tool for understanding the chemical literature landscape.
  • This approach can stimulate innovation in drug design and discovery.
  • Subject librarians should incorporate research gap identification training into chemistry curricula.