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Updated: Jan 20, 2026

An Anaerobic Biosensor Assay for the Detection of Mercury and Cadmium
Published on: December 17, 2018
Optical Sensor Assistant with Voltage Enrichment for Ultrasensitive Detection of Mercury Ions
Xuejian Zheng1, Ling Zhang1,2, Luyi Huang1
1Shanghai Key Laboratory of Modern Optical System, Engineering Research Center of Optical Instrument and System (Ministry of Education), School of Optical-Electrical and Computer Engineering, University of Shanghai for Science and Technology, Shanghai 200093, People's Republic of China.
Abstract:
Voltage enrichment-assisted surface-enhanced resonance Raman scattering (SERRS) was employed for monitoring mercury(II) ions based on a nanoporous gold (NPG)/aptamer hybrid sensor. The hybrid sensor based on the coordination chemistry of thymine-Hg2+-thymine interaction and an applied voltage that pushed mercury ions toward the NPG film improved both the speed and sensitivity of Hg2+ ion detection. The detection limit can reach 0.1 pM, even in the aqueous solution containing 13 metal ions, and the sensor also possesses a fine reproducibility and stability, promising great potential in real-time sensing applications.
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