Fluorescence Optosensing of Triclosan by Upconversion Nanoparticles with Potassium Permanganate

It is greatly significant to develop a simple and rapid sensing method for triclosan (TCS) because it is a widely used and a chronically toxic compound that adversely affects biological organisms and human health. This paper presents the design and development of a novel simple optosensor that uses carboxylic group-functionalized NaYF₄:Yb³⁺/Er³⁺ upconversion nanoparticles (UCNPs) coated with potassium permanganate (KMnO₄). The sensor enables the rapid, non-autofluorescence, sensitive, and selective detection of TCS based on the "turn off-on fluorescence" technique through fluorescence resonance energy transfer. Under an near-infrared radiation excitation (980 nm), the "turn-off fluorescence" process involves the transfer of fluorescence resonance energy between the UCNPs and KMnO₄, whereas the "turn-on fluorescence" process occurs when KMnO₄ is reduced in the presence of TCS. TCS was detected by recovering the green emission of UCNPs. Under optimized conditions, the resulting sensor offered an excellent response to TCS with 0.2 μM of a limit of detection. The developed sensor showed higher selectivity to TCS than other phenolic compounds. Moreover, the analytical performance of the proposed probe was practically demonstrated to successfully monitor trace levels of TCS in samples of tap water and personal care products. The developed simple and sensitive method may offer a new approach for determining TCS in environmental applications.