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Related Concept Videos

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase07:27

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The fate of the replisome following a collision with a head-on RNA polymerase (RNAP) is unknown. We find that the replisome stalls upon collision with a head-on RNAP, but resumes elongation after displacing the RNAP from DNA. Mfd promotes replication restart by facilitating displacement of the RNAP after the...
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Related Experiment Video

Updated: Jan 20, 2026

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase
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In Reply to Boucharel

Michael Gottlieb1, Sara M Krzyzaniak, Teresa M Chan

  • 1Chief academic officer, Academic Life in Emergency Medicine Faculty Incubator, and assistant professor and director of emergency ultrasound, Department of Emergency Medicine, Rush University Medical Center, Chicago, Illinois; ORCID: https://orcid.org/0000-0003-3276-8375. Chief operating officer, Academic Life in Emergency Medicine Faculty Incubator, and clinical assistant professor, Department of Emergency Medicine, and assistant program director, Emergency Medicine Residency, University of Illinois College of Medicine Peoria, Peoria, Illinois; ORCID: https://orcid.org/0000-0002-8173-2750. Chief strategic officer, Academic Life in Emergency Medicine Faculty Incubator, and associate professor, Division of Emergency Medicine, Department of Medicine, McMaster University, Hamilton, Ontario, Canada; teresa.chan@medportal.ca; ORCID: https://orcid.org/0000-0001-6104-462X.

Academic Medicine : Journal of the Association of American Medical Colleges
|August 29, 2019
PubMed
Summary

No abstract available in PubMed .

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