Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endotracheal Intubation of Rabbits Using a Polypropylene Guide Catheter05:46

Endotracheal Intubation of Rabbits Using a Polypropylene Guide Catheter

34.9K
Endotracheal intubation in rabbits is challenging due to their unusual anatomy. Here we present a technique for direct intubation of the trachea using a polypropylene catheter as a guide. This method utilizes relatively inexpensive supplies, requires minimal training, and can be easily performed in any clinical...
34.9K
A Practical Guide to Phylogenetics for Nonexperts12:00

A Practical Guide to Phylogenetics for Nonexperts

36.0K
Here we describe a step-by-step pipeline for generating reliable phylogenies from nucleotide or amino acid sequence datasets. This guide aims to serve researchers or students new to phylogenetic...
36.0K
Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function10:28

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function

5.8K
The purpose of this practical guide is to provide information on the preparation and administration of an interventional diagnostic procedure in clinical practice. It discusses some key preparation and safety considerations, as well as tips for procedural...
5.8K
A Practical Guide for the Production and PET/CT Imaging of 68Ga-DOTATATE for Neuroendocrine Tumors in Daily Clinical Practice08:55

A Practical Guide for the Production and PET/CT Imaging of 68Ga-DOTATATE for Neuroendocrine Tumors in Daily Clinical Practice

18.8K
Well-differentiated neuroendocrine tumors overexpress somatostatin receptors which can be utilized for diagnostic imaging with the radiolabeled somatostatin analog 68Ga-DOTATATE. This protocol details the radiolabeling of 68Ga-DOTATATE, quality control, patient preparation, and subsequent PET/CT imaging. Radiation safety and time constrictions due to the short half-life of 68Ga are taken into...
18.8K
Lavage-induced Surfactant Depletion in Pigs As a Model of the Acute Respiratory Distress Syndrome (ARDS)07:20

Lavage-induced Surfactant Depletion in Pigs As a Model of the Acute Respiratory Distress Syndrome (ARDS)

11.6K
Repeated pulmonary lavages in anesthetized pigs induce lung injury resembling major aspects of human acute respiratory distress syndrome (ARDS). For this purpose the lungs are repeatedly lavaged with 0.9% saline at 37 °C. The goal of the protocol is a reproducible mitigation of gas exchange and hemodynamics for research in...
11.6K
Use of Micropipette-Guided Drug Administration as an Alternative Method to Oral Gavage in Rodent Models02:44

Use of Micropipette-Guided Drug Administration as an Alternative Method to Oral Gavage in Rodent Models

2.7K
Here, we describe micropipette-guided drug administration (MDA) as an alternative method to oral gavage that incentivizes the research animal to ingest treatments readily with minimal stress and discomfort.
2.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The impact of central venous catheter use on long-term growth and neurobehavioral outcome in preterm children born < 29 weeks of gestation.

Molecular and cellular pediatrics·2026
Same author

Extended Barrier Precautions vs Hand Hygiene Alone and Neonatal Sepsis in Intensive Care Patients: The BALTIC Cluster-Randomized Clinical Trial.

JAMA network open·2026
Same author

Sepsis profile among preterm infants with enterostomy and fecal transfer: a multicenter retrospective cohort study.

Molecular and cellular pediatrics·2026
Same author

Risk factors and outcomes of delayed completion of the hexavalent 3 + 1 immunisation series in German preterm infants - an observational study.

Molecular and cellular pediatrics·2026
Same author

Predictive value of increased C-reactive protein levels in preterm infants on respiratory function at five to six years of age.

Communications medicine·2026
Same author

Change in early respiratory management of infants born at less than 30 weeks' gestation in England and Wales: an observational cohort study.

Archives of disease in childhood. Fetal and neonatal edition·2026

Related Experiment Video

Updated: Jan 20, 2026

Endotracheal Intubation of Rabbits Using a Polypropylene Guide Catheter
05:46

Endotracheal Intubation of Rabbits Using a Polypropylene Guide Catheter

Published on: November 13, 2017

34.9K

Surfactant Administration via Thin Catheter: A Practical Guide.

Maximo Vento1,2, Kajsa Bohlin3, Egbert Herting4

  • 1Neonatal Research Group, Health Research Institute La Fe, Valencia, Spain, maximo.vento@uv.es.

Neonatology
|August 29, 2019
PubMed
Summary

Thin catheter surfactant administration is a minimally invasive, effective therapy for preterm infant respiratory distress syndrome. This method is increasingly used in neonatal intensive care units worldwide as an alternative to standard surfactant delivery.

Keywords:
Less invasive surfactant administrationPrematurityRespiratory distress syndromeThin catheter

More Related Videos

A Practical Guide to Phylogenetics for Nonexperts
12:00

A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

36.0K
Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
10:28

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function

Published on: March 15, 2022

5.8K

Related Experiment Videos

Last Updated: Jan 20, 2026

Endotracheal Intubation of Rabbits Using a Polypropylene Guide Catheter
05:46

Endotracheal Intubation of Rabbits Using a Polypropylene Guide Catheter

Published on: November 13, 2017

34.9K
A Practical Guide to Phylogenetics for Nonexperts
12:00

A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

36.0K
Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
10:28

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function

Published on: March 15, 2022

5.8K

Area of Science:

  • Neonatology
  • Pulmonology
  • Biomedical Engineering

Background:

  • Exogenous surfactant replacement is the standard evidence-based therapy for respiratory distress syndrome (RDS) in preterm infants.
  • Administration techniques have evolved towards less invasive methods supporting spontaneous respiration and continuous positive airway pressure (CPAP).
  • While aerosolization and laryngeal mask delivery are under research, they lack widespread clinical adoption.

Purpose of the Study:

  • To provide a contemporary review of surfactant administration via thin catheter.
  • To offer a practical guide reflecting clinical opinions on this evolving method.
  • To highlight thin catheter surfactant delivery as an alternative to standard surfactant administration.

Main Methods:

  • Review of current literature and clinical practices regarding thin catheter surfactant administration.
  • Compilation of scientific opinions from clinicians involved in developing the practical guide.
  • Analysis of various devices used for thin catheter surfactant delivery, including nasogastric tubes and purpose-built catheters.

Main Results:

  • Thin catheter surfactant administration is gaining widespread use in neonatal intensive care units globally.
  • It is recognized as a viable alternative to conventional surfactant delivery methods.
  • Diverse devices are employed for this technique, demonstrating its adaptability.

Conclusions:

  • Thin catheter surfactant administration represents a significant advancement in RDS management for preterm infants.
  • This minimally invasive approach effectively delivers surfactant while supporting spontaneous breathing.
  • The increasing adoption and diverse device usage underscore its clinical importance and practicality.