Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Side effects of valproate.

F E Dreifuss1, D H Langer

  • 1Department of Neurology, School of Medicine, University of Virginia, Charlottesville 22908.

The American Journal of Medicine
|January 25, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preface.

Behavioural neurology·2014
Same author

L-carnitine supplementation in childhood epilepsy: current perspectives.

Epilepsia·1998
Same author

A comparison of rectal diazepam gel and placebo for acute repetitive seizures.

The New England journal of medicine·1998
Same author

Epilepsies with partial seizures in childhood.

Journal of child neurology·1998
Same author

Classification of reflex epilepsies and reflex seizures.

Advances in neurology·1998
Same author

Lamotrigine in childhood epilepsies.

Seminars in pediatric neurology·1997
Same journal

GLP-1 Receptor Agonists and Age-related Macular Degeneration Risk in Diabetes or Non-diabetic Obesity: A Retrospective Cohort Study.

The American journal of medicine·2026
Same journal

Marijuana Use and Acute Myocardial Infarction: Mechanistic Insights, Clinical Implications, and Emerging Challenges.

The American journal of medicine·2026
Same journal

Cave Canem - Beware of the Dog.

The American journal of medicine·2026
Same journal

Risk Factors for 30-day Hospital Readmission After Hospital-at-Home Treatment of Acute Pyelonephritis.

The American journal of medicine·2026
Same journal

Mesenteric Panniculitis.

The American journal of medicine·2026
Same journal

Hypercalcemia and hyperferritinemia in a patient with Graves' disease disease.

The American journal of medicine·2026
See all related articles

Choosing the right antiepileptic drug (AED) for epilepsy management involves matching patient needs with drug properties. Valproate

Area of Science:

  • Neurology
  • Pharmacology
  • Clinical Pharmacy

Background:

  • Effective epilepsy management necessitates individualized antiepileptic drug (AED) selection.
  • AED choice often hinges on balancing efficacy with the drug's side-effect profile.
  • Understanding evolving AED side-effect profiles is crucial for optimal patient care.

Purpose of the Study:

  • To provide an updated perspective on the side-effect profile of valproate.
  • To discuss strategies for mitigating valproate's adverse effects in epilepsy treatment.

Main Methods:

  • Review of clinical data and pharmacologic attributes of antiepileptic drugs.
  • Analysis of factors influencing the emergence and perception of drug side effects.
  • Evaluation of specific interventions for managing valproate-associated adverse events.

Related Experiment Videos

Main Results:

  • Valproate's side-effect profile can be managed through careful patient selection and monitoring.
  • Improved drug formulations and therapeutic drug monitoring can reduce adverse events.
  • Identifying high-risk patients helps minimize the occurrence of serious side effects.

Conclusions:

  • Individualized AED selection remains paramount in epilepsy care.
  • Proactive management strategies can significantly reduce the frequency and severity of valproate side effects.
  • Continuous evaluation of AED safety data is essential for refining treatment guidelines.